| Title: | Relation between total shock energy and mortality in patients with implantable cardioverter-defibrillator |
| Authors: | Tenma, Taro Browse this author |
| Yokoshiki, Hisashi Browse this author →KAKEN DB |
| Mitsuyama, Hirofumi Browse this author |
| Watanabe, Masaya Browse this author |
| Mizukami, Kazuya Browse this author |
| Kamada, Rui Browse this author |
| Takahashi, Masayuki Browse this author |
| Sasaki, Ryo Browse this author |
| Maeno, Motoki Browse this author |
| Okamoto, Kaori Browse this author |
| Chiba, Yuki Browse this author |
| Anzai, Toshihisa Browse this author |
| Keywords: | Total shock energy |
| Implantable cardioverter-defibrillator |
| Mortality |
| Shock accumulation |
| Low left ventricular ejection fraction |
| Atrial fibrillation |
| Issue Date: | 15-May-2018 |
| Publisher: | Elsevier |
| Journal Title: | International journal of cardiology |
| Volume: | 259 |
| Start Page: | 94 |
| End Page: | 99 |
| Publisher DOI: | 10.1016/j.ijcard.2018.02.063 |
| Abstract: | Background: Implantable Cardioverter-Defibrillator (ICD) shocks have been associated with mortality. However, no study has examined the relation between total shock energy and mortality. The aim of this study is to assess the association of total shock energy with mortality, and to determine the patients who are at risk of this association. Methods: Data from 316 consecutive patients who underwent initial ICD implantation in our hospital between 2000 and 2011 were retrospectively studied. We collected shock energy for 3 years from the ICD implantation, and determined the relation of shock energy on mortality after adjusting confounding factors. Results: Eighty-seven ICD recipients experienced shock(s) within 3 years from ICD implantation and 43 patients had died during the follow-up. The amount of shock energy was significantly associated with all-cause death [adjusted hazard ratio (HR) 1.26 (per 100 joule increase), p < 0.01] and tended to be associated with cardiac death (adjusted HR 1.30, p = 0.08). The survival rate of patients with high shock energy accumulation (>= 182 joule) was lower (p = 0.05), as compared to low shock energy accumulation (<182 joule), likewise to no shock. Besides, the relation between high shock energy accumulation and all-cause death was remarkable in the patients with low left ventricular ejection fraction (LVEF <= 40%) or atrial fibrillation (AF). Conclusions: Increase of shock energywas related tomortality in ICD recipients. This relation was evident in patients with low LVEF or AF. |
| Rights: | © 2018. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ |
| http://creativecommons.org/licenses/by-nc-nd/4.0/ |
| Type: | article (author version) |
| URI: | http://hdl.handle.net/2115/74003 |
| Appears in Collections: | 医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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