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Detection of novel gammaherpesviruses from fruit bats in Indonesia

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Please use this identifier to cite or link to this item:http://hdl.handle.net/2115/74394

Title: Detection of novel gammaherpesviruses from fruit bats in Indonesia
Authors: Wada, Yuji Browse this author
Sasaki, Michihito Browse this author →KAKEN DB
Setiyono, Agus Browse this author
Handharyani, Ekowati Browse this author
Rahmadani, Ibenu Browse this author
Taha, Siswatiana Browse this author
Adiani, Sri Browse this author
Latief, Munira Browse this author
Kholilullah, Zainal Abidin Browse this author
Subangkit, Mawar Browse this author
Kobayashi, Shintaro Browse this author →KAKEN DB
Nakamura, Ichiro Browse this author →KAKEN DB
Kimura, Takashi Browse this author →KAKEN DB
Orba, Yasuko Browse this author →KAKEN DB
Sawa, Hirofumi Browse this author →KAKEN DB
Keywords: Gammaherpesvirus
Fruit bat
PCR screening
Long-distance PCR
Phylogenetic analysis
Issue Date: Mar-2018
Publisher: Society for General Microbiology
Journal Title: Journal of medical microbiology
Volume: 67
Issue: 3
Start Page: 415
End Page: 422
Publisher DOI: 10.1099/jmm.0.000689
Abstract: Bats are an important natural reservoir of zoonotic viral pathogens. We previously isolated an alphaherpesvirus in fruit bats in Indonesia, and here establish the presence of viruses belonging to other taxa of the family Herpesviridae. We screened the same fruit bat population with pan-herpesvirus PCR and discovered 68 sequences of novel gammaherpesvirus, designated 'megabat gammaherpesvirus' (MgGHV). A phylogenetic analysis of approximately 3.4 kbp of continuous MgGHV sequences encompassing the glycoprotein B gene and DNA polymerase gene revealed that the MgGHV sequences are distinct from those of other reported gammaherpesviruses. Further analysis suggested the existence of co-infections of herpesviruses in Indonesian fruit bats. Our findings extend our understanding of the infectious cycles of herpesviruses in bats in Indonesia and the phylogenetic diversity of the gammaherpesviruses.
Type: article (author version)
URI: http://hdl.handle.net/2115/74394
Appears in Collections:人獣共通感染症リサーチセンター (Research Center for Zoonosis Control) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
国際連携研究教育局 : GI-CoRE (Global Institution for Collaborative Research and Education : GI-CoRE) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 澤 洋文

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