Title: | Detection of novel gammaherpesviruses from fruit bats in Indonesia |
Authors: | Wada, Yuji Browse this author |
Sasaki, Michihito Browse this author →KAKEN DB |
Setiyono, Agus Browse this author |
Handharyani, Ekowati Browse this author |
Rahmadani, Ibenu Browse this author |
Taha, Siswatiana Browse this author |
Adiani, Sri Browse this author |
Latief, Munira Browse this author |
Kholilullah, Zainal Abidin Browse this author |
Subangkit, Mawar Browse this author |
Kobayashi, Shintaro Browse this author →KAKEN DB |
Nakamura, Ichiro Browse this author →KAKEN DB |
Kimura, Takashi Browse this author →KAKEN DB |
Orba, Yasuko Browse this author →KAKEN DB |
Sawa, Hirofumi Browse this author →KAKEN DB |
Keywords: | Gammaherpesvirus |
Fruit bat |
PCR screening |
Long-distance PCR |
Phylogenetic analysis |
Issue Date: | Mar-2018 |
Publisher: | Society for General Microbiology |
Journal Title: | Journal of medical microbiology |
Volume: | 67 |
Issue: | 3 |
Start Page: | 415 |
End Page: | 422 |
Publisher DOI: | 10.1099/jmm.0.000689 |
Abstract: | Bats are an important natural reservoir of zoonotic viral pathogens. We previously isolated an alphaherpesvirus in fruit bats in Indonesia, and here establish the presence of viruses belonging to other taxa of the family Herpesviridae. We screened the same fruit bat population with pan-herpesvirus PCR and discovered 68 sequences of novel gammaherpesvirus, designated 'megabat gammaherpesvirus' (MgGHV). A phylogenetic analysis of approximately 3.4 kbp of continuous MgGHV sequences encompassing the glycoprotein B gene and DNA polymerase gene revealed that the MgGHV sequences are distinct from those of other reported gammaherpesviruses. Further analysis suggested the existence of co-infections of herpesviruses in Indonesian fruit bats. Our findings extend our understanding of the infectious cycles of herpesviruses in bats in Indonesia and the phylogenetic diversity of the gammaherpesviruses. |
Type: | article (author version) |
URI: | http://hdl.handle.net/2115/74394 |
Appears in Collections: | 人獣共通感染症国際共同研究所 (International Institute for Zoonosis Control) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc) 国際連携研究教育局 : GI-CoRE (Global Institution for Collaborative Research and Education : GI-CoRE) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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