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Hokkaido University Collection of Scholarly and Academic Papers >
Graduate School of Agriculture / Faculty of Agriculture >
Peer-reviewed Journal Articles, etc >
Intestinal α-Glucosidase Inhibitors in Achillea millefolium
| Title: | Intestinal α-Glucosidase Inhibitors in Achillea millefolium |
| Authors: | Noda, Kota Browse this author | | Kato, Eisuke Browse this author →KAKEN DB | | Kawabata, Jun Browse this author →KAKEN DB |
| Keywords: | Diabetes | | Intestinal α-glucosidase | | Maltase | | Glucosidase inhibitor | | Caffeoylquinic acid |
| Issue Date: | 1-Aug-2017 |
| Publisher: | SAGE |
| Journal Title: | Natural Product Communications |
| Volume: | 12 |
| Issue: | 8 |
| Start Page: | 1259 |
| End Page: | 1261 |
| Publisher DOI: | 10.1177/1934578X1701200828 |
| Abstract: | Achillea millefolium is a plant used as a component of anti-diabetic preparation but the bioactive compounds responsible for its use are not known. Inhibition of intestinal α-glucosidase is a preferable effect for prevention and treatment of diabetes, and A. millefolium extract showed inhibitory activity against the enzyme. Activity-guided separation of the extract gave four mono- or di-caffeoylquinic acids as the isolate. Quantitation of these four caffeoylquinic acids and the activity of the isolates suggested that these are the major contributor for the α-glucosidase inhibitory activity in the extract. However also, the presence of unidentified, minor, but potent α-glucosidase inhibitor in the isolate was also suggested. |
| Rights: | Kota Noda, Eisuke Kato, Jun Kawabata, Intestinal α-Glucosidase Inhibitors in Achillea millefolium, Natural Product Communications (Vol12 No.8) pp. 1259-1261. Copyright © 2017(SAGE). DOI:10.1177/1934578X1701200828. |
| Type: | article (author version) |
| URI: | http://hdl.handle.net/2115/75147 |
| Appears in Collections: | 農学院・農学研究院 (Graduate School of Agriculture / Faculty of Agriculture) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 加藤 英介
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