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Bioactive micropatterning of apatite immobilizing cell adhesion protein by laser-induced forward transfer with a shock absorber
Title: | Bioactive micropatterning of apatite immobilizing cell adhesion protein by laser-induced forward transfer with a shock absorber |
Authors: | Narazaki, Aiko Browse this author | Oyane, Ayako Browse this author | Komuro, Saki Browse this author | Kurosaki, Ryozo Browse this author | Kameyama, Tomoko Browse this author | Sakamaki, Ikuko Browse this author | Araki, Hiroko Browse this author | Miyaji, Hirofumi Browse this author →KAKEN DB |
Issue Date: | 1-Jul-2019 |
Publisher: | Optical Society of America |
Journal Title: | Optical materials express |
Volume: | 9 |
Issue: | 7 |
Start Page: | 2807 |
End Page: | 2816 |
Publisher DOI: | 10.1364/OME.9.002807 |
Abstract: | The additive patterning of apatite with good biocompatibility and osteoconductivity is a useful technique for the production and surface functionalization of biomaterials. We developed this technique through our laser-induced forward transfer (LIFT) process using a laser-absorbing sacrificial layer in combination with a shock-absorbing polydimethylsiloxane (PDMS) receiver. With the PDMS shock-absorbing function, even the brittle apatite and that immobilizing the cell adhesion protein fibronectin (Fn-apatite) were successfully transferred and micropatterned while maintaining their dense, filmy state. The laser pulse energy effect was investigated, leading to the optimum energy range just above the transfer threshold. The apatite and Fn-apatite micropatterns exhibited superior cytocompatibility compared to the PDMS surface, and could potentially be used for cellular micromanipulation. (C) 2019 Optical Society of America under the terms of the OSA Open Access Publishing Agreement |
Rights: | © 2019 Optical Society of America. Users may use, reuse, and build upon the article, or use the article for text or data mining, so long as such uses are for non-commercial purposes and appropriate attribution is maintained. All other rights are reserved. |
Type: | article |
URI: | http://hdl.handle.net/2115/75150 |
Appears in Collections: | 歯学院・歯学研究院 (Graduate School of Dental Medicine / Faculty of Dental Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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