| Title: | Clinical Evaluation of QuickNaviTM-Ebola in the 2018 Outbreak of Ebola Virus Disease in the Democratic Republic of the Congo |
| Authors: | Makiala, Sheila Browse this author |
| Mukadi, Daniel Browse this author |
| De Weggheleire, Anja Browse this author |
| Muramatsu, Shino Browse this author |
| Kato, Daisuke Browse this author |
| Inano, Koichi Browse this author |
| Gondaira, Fumio Browse this author |
| Kajihara, Masahiro Browse this author →KAKEN DB |
| Yoshida, Reiko Browse this author →KAKEN DB |
| Changula, Katendi Browse this author |
| Mweene, Aaron Browse this author |
| Mbala-Kingebeni, Placide Browse this author |
| Muyembe-Tamfum, Jean-Jacques Browse this author |
| Masumu, Justin Browse this author |
| Ahuka, Steve Browse this author |
| Takada, Ayato Browse this author →KAKEN DB |
| Keywords: | Ebola virus |
| EVD |
| rapid diagnostic test |
| immunochromatography |
| QuickNavi |
| DRC |
| Issue Date: | Jul-2019 |
| Publisher: | MDPI |
| Journal Title: | Viruses |
| Volume: | 11 |
| Issue: | 7 |
| Start Page: | 589 |
| Publisher DOI: | 10.3390/v11070589 |
| PMID: | 31261668 |
| Abstract: | The recent large outbreaks of Ebola virus disease (EVD) in West Africa and the Democratic Republic of the Congo (DRC) have highlighted the need for rapid diagnostic tests to control this disease. In this study, we clinically evaluated a previously developed immunochromatography-based kit, QuickNavi(TM)-Ebola. During the 2018 outbreaks in DRC, 928 blood samples from EVD-suspected cases were tested with QuickNavi(TM)-Ebola and the WHO-approved GeneXpert. The sensitivity and specificity of QuickNavi(TM)-Ebola, estimated by comparing it to GeneXpert-confirmed cases, were 85% (68/80) and 99.8% (846/848), respectively. These results indicate the practical reliability of QuickNavi(TM)-Ebola for point-of-care diagnosis of EVD. |
| Rights: | © 2019 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/). |
| https://creativecommons.org/licenses/by/4.0/ |
| Type: | article |
| URI: | http://hdl.handle.net/2115/75467 |
| Appears in Collections: | 人獣共通感染症国際共同研究所 (International Institute for Zoonosis Control) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
国際連携研究教育局 : GI-CoRE (Global Institution for Collaborative Research and Education : GI-CoRE) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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