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Volume 67 Number 3 >

Effect of ultra low fat diet on regulatory T cells of dogs with intestinal limphangiectasia secondary to chronic enteropathy: A pilot study

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Please use this identifier to cite or link to this item:http://doi.org/10.14943/jjvr.67.3.221

Title: Effect of ultra low fat diet on regulatory T cells of dogs with intestinal limphangiectasia secondary to chronic enteropathy: A pilot study
Authors: Nisa, Khoirun Browse this author
Ohta, Hiroshi Browse this author →KAKEN DB
Yokoyama, Nozomu Browse this author
Tamura, Masahiro Browse this author
Nagata, Noriyuki Browse this author
Sasaoka, Kazuyoshi Browse this author
Dermlim, Angkhana Browse this author
Leela-Arporn, Rommaneeya Browse this author
Morita, Tomoya Browse this author
Osuga, Tatsuyuki Browse this author
Sasaki, Noboru Browse this author →KAKEN DB
Morishita, Keitaro Browse this author →KAKEN DB
Nakamura, Kensuke Browse this author →KAKEN DB
Kagawa, Yumiko Browse this author
Takiguchi, Mitsuyoshi Browse this author →KAKEN DB
Keywords: IL-CE
Treg
ULFD
Issue Date: Aug-2019
Publisher: Faculty of Veterinary Medicine, Hokkaido University
Journal Title: Japanese Journal of Veterinary Research
Volume: 67
Issue: 3
Start Page: 221
End Page: 227
Abstract: Ultra low fat diet (ULFD) has shown a good therapeutic effect in dogs with intestinal lymphangiectasia secondary to CE (IL-CE). As we hypothesized that the mechanism of ULFD may involve the resolution of immunological impairment in IL-CE dogs, our study aimed to investigate the effect of ULFD on the circulating regulatory T cell (Treg) of IL-CE dogs. Treg frequency of pre- and post-ULFD blood samples from dogs with IL-CE (n = 3) were measured using flow cytometry. Treg frequency in IL-CE group before ULFD treatment showed lower tendency when compared to healthy control (mean±SD; 2.0±1.6% and 4.3±1.4%, respectively), and showed increased tendency after ULFD (mean±SD; 4.5±3.5%). The results suggested that ULFD might restore circulating Treg frequency of IL-CE dogs.
Type: bulletin (article)
URI: http://hdl.handle.net/2115/75488
Appears in Collections:Japanese Journal of Veterinary Research > Volume 67 Number 3

Submitter: 獣医学部図書室

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