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Volume 67 Number 3 >

A clinical case of enzootic bovine leukosis diagnosed by malignant lymphoma cells detected in urinary sediment

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Title: A clinical case of enzootic bovine leukosis diagnosed by malignant lymphoma cells detected in urinary sediment
Authors: Sakaguchi, Kana Browse this author
Ougitani, Manabu Browse this author
Maezawa, Masaki Browse this author
Tanaka, Yusuke Browse this author
Watanabe, Ken-ichi Browse this author →KAKEN DB
Horiuchi, Noriyuki Browse this author →KAKEN DB
Kobayashi, Yoshiyasu Browse this author →KAKEN DB
Inokuma, Hisashi Browse this author →KAKEN DB
Keywords: clinical diagnosis
enzootic bovine leukosis
urinary sediment
Issue Date: Aug-2019
Publisher: Faculty of Veterinary Medicine, Hokkaido University
Journal Title: Japanese Journal of Veterinary Research
Volume: 67
Issue: 3
Start Page: 229
End Page: 233
Abstract: A Holstein cow presented with decreased milk production. Rectal palpation revealed masses in the pelvic cavity without enlargement of superficial lymph nodes. The cow maintained a continuing urination posture after urination and yellow cloudy urine drops were observed. Cytology of urine sediment revealed large atypical lymphoid cells suggestive of lymphoma. Hematology examination showed lymphocytosis with atypical lymphocytes. Increased activities of serum lactate dehydrogenase and thymidine kinase were also suggestive of lymphoma. PCR for bovine leukemia virus was positive. B-cell clonality PCR to define the rearrangement of immunoglobulin heavy chain revealed monoclonal growth of B-cells. These findings led to a diagnosis of enzootic bovine leukosis (EBL). Examination of urinary sediment can be diagnostic for EBL with lesions in the urinary system.
Type: bulletin (article)
Appears in Collections:Japanese Journal of Veterinary Research > Volume 67 Number 3

Submitter: 獣医学部図書室

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