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POEMS Syndrome Showing Left Ventricular Dysfunction and Extracellular Edema Assessed by Cardiac Magnetic Resonance Imaging
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| Title: | POEMS Syndrome Showing Left Ventricular Dysfunction and Extracellular Edema Assessed by Cardiac Magnetic Resonance Imaging |
| Authors: | Takahashi, Yumi Browse this author | | Iwano, Hiroyuki Browse this author →KAKEN DB | | Nakano, Ippei Browse this author | | Fukushima, Arata Browse this author →KAKEN DB | | Naya, Masanao Browse this author →KAKEN DB | | Shimizu, Ai Browse this author | | Matsuno, Yoshihiro Browse this author →KAKEN DB | | Oyama-Manabe, Noriko Browse this author →KAKEN DB | | Anzai, Toshihisa Browse this author →KAKEN DB |
| Keywords: | POEMS syndrome | | vascular endothelial growth factor | | native T1 mapping | | extracellular volume |
| Issue Date: | 23-Oct-2019 |
| Publisher: | 日本内科学会 |
| Journal Title: | Internal medicine |
| Volume: | 58 |
| Issue: | 17 |
| Start Page: | 2539 |
| End Page: | 2543 |
| Publisher DOI: | 10.2169/internalmedicine.2842-19 |
| Abstract: | Although cardiac involvement is rare in polyneuropathy, organomegaly, endocrinopathy, M protein, and skin changes (POEMS) syndrome, the clinical course becomes considerably worse on complication with cardiac lesions. The increased release of various cytokines has been observed in the pathogenesis of POEMS syndrome, and serum vascular endothelial growth factor (VEGF) levels are known to be associated with the disease activity. We herein report a patient with POEMS syndrome who showed left ventricular systolic dysfunction and was treated with lenalidmide therapy. Of note, the reduction in extracellular edema in the left ventricular wall was clearly visualized by changes in the native T1 values and extracellular volumes on cardiac magnetic resonance imaging. |
| Rights: | https://creativecommons.org/licenses/by-nc-nd/4.0/ |
| Type: | article |
| URI: | http://hdl.handle.net/2115/75842 |
| Appears in Collections: | 国際連携研究教育局 : GI-CoRE (Global Institution for Collaborative Research and Education : GI-CoRE) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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