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Evaluation Of Subjective Cognitive Function Using The Cognitive Complaints In Bipolar Disorder Rating Assessment (COBRA) In Japanese Adults

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Title: Evaluation Of Subjective Cognitive Function Using The Cognitive Complaints In Bipolar Disorder Rating Assessment (COBRA) In Japanese Adults
Authors: Toyoshima, Kuniyoshi Browse this author
Inoue, Takeshi Browse this author →KAKEN DB
Masuya, Jiro Browse this author →KAKEN DB
Ichiki, Masahiko Browse this author →KAKEN DB
Fujimura, Yota Browse this author
Kusumi, Ichiro Browse this author →KAKEN DB
Keywords: 8-item Short-Form Health Survey
Sheehan Disability Scale
Patient Health Questionnaire-9
subjective cognitive dysfunction
Issue Date: 26-Nov-2019
Publisher: Dove Medical Press
Journal Title: Neuropsychiatric Disease and Treatment
Volume: 15
Start Page: 2981
End Page: 2990
Publisher DOI: 10.2147/NDT.S218382
Abstract: Purpose: To examine the relationship between depressive symptoms, subjective cognitive function, and quality of life in Japanese adults using the Cognitive Complaints in Bipolar Disorder Rating Assessment (COBRA). Patients and methods: We evaluated 585 adult community volunteers using the Patient Health Questionnaire-9 (PHQ-9) for evaluation of depressive symptoms and the COBRA for evaluation of subjective cognitive function. We additionally used the 8-item Short-Form Health Survey and the Sheehan Disability Scale to evaluate the quality of life (QoL). Results: Measures of subjective cognitive function were significantly correlated with depressive symptoms and QoL. Structural equation modeling demonstrated that depressive symptoms directly and indirectly decreased QoL via their effects on subjective cognitive dysfunction. Measures of depressive symptoms were more closely related to QoL than were measures of subjective cognitive function. Limitations: Study participants were general adult population community volunteers and included healthy people; thus, these results may not be generalizable to patients with depression or bipolar disorder. In addition, the cross-sectional design of this study prevented the identification of causal relationships among the parameters. Conclusion: Changes in subjective cognitive function may affect QoL via depressive symptoms. Evaluations of subjective cognitive function may help identify factors that reduce QoL.
Type: article
Appears in Collections:医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

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