| Title: | Seroprevalence of filovirus infection of Rousettus aegyptiacus bats in Zambia |
| Authors: | Changula, Katendi1 Browse this author |
| Kajihara, Masahiro2 Browse this author →KAKEN DB |
| Mori, Akina3 Browse this author |
| Eto, Yoshiki4 Browse this author |
| Miyamoto, Hiroko5 Browse this author |
| Yoshida, Reiko6 Browse this author →KAKEN DB |
| Shigeno, Asako7 Browse this author |
| Hang'ombe, Bernard8 Browse this author |
| Qiu, Yongjin9 Browse this author |
| Mwizabi, Daniel10 Browse this author |
| Squarre, David11 Browse this author |
| Ndebe, Joseph12 Browse this author |
| Ogawa, Hirohito13 Browse this author →KAKEN DB |
| Harima, Hayato14 Browse this author |
| Simulundu, Edgar15 Browse this author |
| Moonga, Ladslav16 Browse this author |
| Kapila, Penjaninge17 Browse this author |
| Furuyama, Wakako18 Browse this author |
| Kondoh, Tatsunari19 Browse this author |
| Sato, Masahiro20 Browse this author |
| Takadate, Yoshihiro21 Browse this author |
| Kaneko, Chiho22 Browse this author |
| Nakao, Ryo23 Browse this author →KAKEN DB |
| Mukonka, Victor24 Browse this author |
| Mweene, Aaron25 Browse this author |
| Takada, Ayato26 Browse this author →KAKEN DB |
| Authors(alt): | Kajihara, Akina3 |
| Keywords: | Filovirus |
| Fruit bats |
| ELISA |
| Marburgvirus |
| Issue Date: | 15-Dec-2018 |
| Publisher: | Oxford University Press |
| Journal Title: | Journal of Infectious Diseases |
| Volume: | 218 |
| Issue: | suppl 5 |
| Start Page: | S312 |
| End Page: | S317 |
| Publisher DOI: | 10.1093/infdis/jiy266 |
| PMID: | 29889270 |
| Abstract: | Bats are suspected to play important roles in the ecology of filoviruses, including ebolaviruses and marburgviruses. A cave-dwelling fruit bat, Rousettus aegyptiacus, has been shown to be a reservoir of marburgviruses. Using an enzyme-linked immunosorbent assay with the viral glycoprotein antigen, we detected immunoglobulin G antibodies specific to multiple filoviruses in 158 of 290 serum samples of R aegyptiacus bats captured in Zambia during the years 2014-2017. In particular, 43.8% of the bats were seropositive to marburgvirus, supporting the notion that this bat species continuously maintains marburgviruses as a reservoir. Of note, distinct peaks of seropositive rates were repeatedly observed at the beginning of rainy seasons, suggesting seasonality of the presence of newly infected individuals in this bat population. These data highlight the need for continued monitoring of filovirus infection in this bat species even in countries where filovirus diseases have not been reported. |
| Rights: | This is a pre-copyedited, author-produced version of an article accepted for publication in The Journal of Infectious Diseases following peer review. The version of record Volume 218 Issue suppl_5, S312–S317, 2018 is available online at: https://doi.org/10.1093/infdis/jiy266. |
| Type: | article (author version) |
| URI: | http://hdl.handle.net/2115/76335 |
| Appears in Collections: | 人獣共通感染症国際共同研究所 (International Institute for Zoonosis Control) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
国際連携研究教育局 : GI-CoRE (Global Institution for Collaborative Research and Education : GI-CoRE) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
|
