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Hokkaido University Collection of Scholarly and Academic Papers >
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Exposures of children to neonicotinoids in pine wilt disease control areas
| Title: | Exposures of children to neonicotinoids in pine wilt disease control areas |
| Authors: | Ikenaka, Yoshinori Browse this author →KAKEN DB | | Miyabara, Yuichi Browse this author | | Ichise, Takahiro Browse this author | | Nakayama, Shouta Browse this author | | Nimako, Collins Browse this author | | Ishizuka, Mayumi Browse this author | | Tohyama, Chiharu Browse this author |
| Keywords: | Insecticide | | Hazard/risk assessment | | Pesticide risk assessment | | Pesticide | | Neonicotinoid | | Children | | Estimated daily intake |
| Issue Date: | Jan-2019 |
| Publisher: | John Wiley & Sons |
| Journal Title: | Environmental toxicology and chemistry |
| Volume: | 38 |
| Issue: | 1 |
| Start Page: | 71 |
| End Page: | 79 |
| Publisher DOI: | 10.1002/etc.4316 |
| Abstract: | Neonicotinoid insecticides that have been on the market since 1992 have been used globally including in Japan. Because they are sprayed over forests and agricultural areas, inadvertent toxicity in nontarget insects (especially honey bees) and humans is a matter of public concern. However, information on exposure levels and potential health impacts of neonicotinoids in children living around sprayed areas is scarce. Thus, we determined neonicotinoid exposure levels in children living in communities where thiacloprid was used to control pine wilt disease. A total of 46 children (23 males and 23 females) were recruited for the present study, and informed written consent was obtained from their guardians. Urine specimens were collected before, during, and after insecticide spraying events; and atmospheric particulate matter was also collected. Concentrations of thiacloprid and 6 other neonicotinoid compounds were determined in urine samples and in atmospheric particulate matter specimens using liquid chromatography-electrospray ionization-tandem mass spectrometry. In urine specimens, thiacloprid concentrations were <0.13 mu g/L and were detectable in approximately 30% of all samples. Concentrations of the other neonicotinoids, N-dm-acetamiprid, thiamethoxam, dinotefuran, and clothianidin, were 18.7, 1.92, 72.3, and 6.02 mu g/L, respectively. Estimated daily intakes of these neonicotinoids were then calculated from urinary levels; although the estimated daily intakes of the neonicotinoids were lower than current acceptable daily intake values, the children were found to be exposed to multiple neonicotinoids on a daily basis. Environ Toxicol Chem 2019;38:71-79. (c) 2018 SETAC |
| Rights: | This is the peer reviewed version of the following article: https://setac.onlinelibrary.wiley.com/doi/full/10.1002/etc.4316, which has been published in final form at http://doi.org/10.1002/etc.4316. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. |
| Type: | article (author version) |
| URI: | http://hdl.handle.net/2115/76482 |
| Appears in Collections: | 獣医学院・獣医学研究院 (Graduate School of Veterinary Medicine / Faculty of Veterinary Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 池中 良徳
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