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Hokkaido University Collection of Scholarly and Academic Papers >
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Development of Taenia saginata asiatica metacestodes in SCID mice and its infectivity in human and alternative definitive hosts
| Title: | Development of Taenia saginata asiatica metacestodes in SCID mice and its infectivity in human and alternative definitive hosts |
| Authors: | Chang, S. L. Browse this author | | Nonaka, N.2 Browse this author →KAKEN DB | | Kamiya, M. Browse this author | | Kanai, Y. Browse this author | | Ooi, H. K. Browse this author | | Chung, W. C. Browse this author | | Oku, Y. Browse this author |
| Authors(alt): | 野中, 成晃2 |
| Keywords: | Taenia saginata asiatica | | Metacestode | | Cysticercus | | SCID mice | | Alternative host | | Human infection |
| Issue Date: | May-2005 |
| Publisher: | Springer-Verlag |
| Journal Title: | Parasitology Research |
| Volume: | 96 |
| Issue: | 2 |
| Start Page: | 95 |
| End Page: | 101 |
| Publisher DOI: | 10.1007/s00436-005-1328-4 |
| PMID: | 15812671 |
| Abstract: | Development of Taenia saginata asiatica metacestodes in SCID mice, and its infectivity in humans, golden hamsters, and Mongolian gerbils as alternative definitive hosts, were investigated. Cysticerci were recovered from SCID mice that were subcutaneously injected with hatched oncospheres of T. s. asiatica. The morphological changes of metacestodes were observed. The recovered cysticerci were fed to gerbils, hamsters and humans, to check for their infectivity. Tapeworms were recovered from gerbils and hamsters fed with 20 to 45 week-old cysticerci, and proglottids excretions were observed in human volunteers fed with 45 week-old cysticerci. However, no tapeworms were recovered from gerbils fed with 10 week-old cysticerci. Our results suggest that T. s. asiatica oncospheres needed more than 20 weeks to develop to maturity in SCID mice to be infective to both their natural and alternative definitive hosts. |
| Rights: | The original publication is available at www.springerlink.com |
| Type: | article (author version) |
| URI: | http://hdl.handle.net/2115/765 |
| Appears in Collections: | 獣医学院・獣医学研究院 (Graduate School of Veterinary Medicine / Faculty of Veterinary Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 野中 成晃
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