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Intramuscular metabolism during low-intensity resistance exercise with blood flow restriction

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Title: Intramuscular metabolism during low-intensity resistance exercise with blood flow restriction
Authors: Suga, Tadashi Browse this author
Okita, Koichi Browse this author
Morita, Noriteru Browse this author →KAKEN DB
Yokota, Takashi Browse this author →KAKEN DB
Hirabayashi, Kagami Browse this author
Horiuchi, Masahiro Browse this author
Takada, Shingo Browse this author →KAKEN DB
Takahashi, Tomohiro Browse this author
Omokawa, Masashi Browse this author
Kinugawa, Shintaro Browse this author →KAKEN DB
Tsutsui, Hiroyuki Browse this author →KAKEN DB
Keywords: training
magnetic resonance spectroscopy
Issue Date: 2009
Publisher: American Physiological Society
Journal Title: Journal of Applied Physiology
Volume: 106
Issue: 4
Start Page: 1119
End Page: 1124
Publisher DOI: 10.1152/japplphysiol.90368.2008
Abstract: Although recent studies have reported that low-intensity resistance training with blood flow restriction could stress the muscle effectively and provide rapid muscle hypertrophy and strength gain equivalent to those of high-intensity resistance training, the exact mechanism and its generality have not yet been clarified. We investigated the intramuscular metabolism during low-intensity resistance exercise with blood flow restriction and compared it with that of high-intensity and low-intensity resistance exercises without blood flow restriction using 31P-magnetic resonance spectroscopy. Twenty-six healthy subjects (22 ± 4 yr) participated and performed unilateral plantar flexion (30 repetitions/min) for 2 min. Protocols were as follows: low-intensity exercise (L) using a load of 20% of one-repetition maximum (1 RM), L with blood flow restriction (LR), and high-intensity exercise using 65% 1 RM (H). Intramuscular phosphocreatine (PCr) and diprotonated phosphate (H2PO4−) levels and intramuscular pH at rest and during exercise were obtained. We found that the PCr depletion, the H2PO4− increase, and the intramuscular pH decrease during LR were significantly greater than those in L (P < 0.001); however, those in LR were significantly lower than those in H (P < 0.001). The recruitment of fast-twitch fiber evaluated by inorganic phosphate splitting occurred in only 31% of the subjects in LR, compared with 70% in H. In conclusion, the metabolic stress in skeletal muscle during low-intensity resistance exercise was significantly increased by applying blood flow restriction, but did not generally reach that during high-intensity resistance exercise. This new method of resistance training needs to be examined for optimization of the protocol to reach equivalence with high-intensity resistance training.
Type: article
Appears in Collections:医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

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