| Title: | Metachronous liver metastases after long-term follow-up of endoscopic resection for rectal neuroendocrine neoplasms : a report of three cases |
| Authors: | Hane, Yuma Browse this author |
| Tsuchikawa, Takahiro Browse this author →KAKEN DB |
| Tanaka, Kimitaka Browse this author →KAKEN DB |
| Nakanishi, Yoshitsugu Browse this author →KAKEN DB |
| Asano, Toshimichi Browse this author →KAKEN DB |
| Noji, Takehiro Browse this author →KAKEN DB |
| Kurashima, Yo Browse this author →KAKEN DB |
| Ebihara, Yuma Browse this author →KAKEN DB |
| Murakami, Soichi Browse this author →KAKEN DB |
| Nakamura, Toru Browse this author →KAKEN DB |
| Okamura, Keisuke Browse this author →KAKEN DB |
| Takeuchi, Satoshi Browse this author |
| Shichinohe, Toshiaki Browse this author →KAKEN DB |
| Hirano, Satoshi Browse this author →KAKEN DB |
| Keywords: | Neuroendocrine neoplasm |
| Endoscopic resection |
| Long-term follow-up |
| Recurrence |
| Issue Date: | 15-Jan-2020 |
| Publisher: | Springer (SpringerOpen) |
| Journal Title: | Surgical case reports |
| Volume: | 6 |
| Issue: | 1 |
| Start Page: | 22 |
| Publisher DOI: | 10.1186/s40792-020-0792-5 |
| PMID: | 31940115 |
| Abstract: | Background Rectal neuroendocrine neoplasms (NENs) are rare, but their incidence has increased in recent years. The metastasis rate is low in cases of a tumor diameter < 1 cm or depth of invasion lower than the submucosa; therefore, the European Neuroendocrine Tumor Society (ENETS) and the North American Neuroendocrine Tumor Society (NANETS) consensus guidelines recommend endoscopic resection. Since little has been reported on the long-term prognosis of endoscopic resection for rectal NEN, consensus is lacking regarding the follow-up period after endoscopic resection. Case presentation Here, we report three cases of metachronous liver metastasis after long-term follow-up of endoscopic mucosal resection (EMR) for rectal NEN. The pathological findings indicated a depth lower than the submucosa and complete radical resection in all cases and lymphovascular invasion in only one case. All three cases showed metachronous multiple liver metastases after 9-13 years of follow-up for EMR, despite achieving complete resection and without muscular invasion. Conclusions Metachronous liver metastases may occur after long interval following endoscopic resection; thus, long-term follow-up is necessary after endoscopic resection for rectal NEN. |
| Rights: | https://creativecommons.org/licenses/by/4.0/ |
| Type: | article |
| URI: | http://hdl.handle.net/2115/76917 |
| Appears in Collections: | 北海道大学病院 (Hokkaido University Hospital) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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