Oxidative stress in cardiac and skeletal muscle dysfunction associated with diabetes mellitus


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Title:	Oxidative stress in cardiac and skeletal muscle dysfunction associated with diabetes mellitus
Authors:	Tsutsui, Hiroyuki Browse this author →KAKEN DB
	Kinugawa, Shintaro Browse this author →KAKEN DB
	Matsushima, Shouji Browse this author →KAKEN DB
	Yokota, Takashi Browse this author →KAKEN DB
Keywords:	oxidative stress
	diabetes mellitus
	cardiac dysfunction
	skeletal muscle dysfunction
	heart failure
Issue Date:	2010
Publisher:	SOCIETY FOR FREE RADICAL RESEARCH JAPAN
Journal Title:	Journal of Clinical Biochemistry and Nutrition
Volume:	48
Issue:	1
Start Page:	68
End Page:	71
Publisher DOI:	10.3164/jcbn.11-012FR
Abstract:	Diabetes mellitus increases the risk of heart failure independently of underlying coronary artery disease. It also causes skeletal muscle dysfunction, which is responsible for reduced exercise capacity commonly seen in heart failure. The underlying pathogenesis is partially understood. Several factors may contribute to the development of cardiac and skeletal muscle dysfunction in heart failure and diabetes mellitus. Based on the findings in animal models, this review discusses the role of oxidative stress that may be involved in the development and progression of cardiac and skeletal dysfunction associated with diabetes.
Type:	article
URI:	http://hdl.handle.net/2115/76940
Appears in Collections:	北海道大学病院 (Hokkaido University Hospital) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

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