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Effects of Atrial Fibrillation on Long-Term Outcomes in Patients Hospitalized for Heart Failure in Japan
This item is licensed under:Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
Title: | Effects of Atrial Fibrillation on Long-Term Outcomes in Patients Hospitalized for Heart Failure in Japan |
Authors: | Hamaguchi, Sanae Browse this author | Yokoshiki, Hisashi Browse this author →KAKEN DB | Kinugawa, Shintaro Browse this author →KAKEN DB | Tsuchihashi-Makaya, Miyuki Browse this author | Yokota, Takashi Browse this author →KAKEN DB | Takeshita, Akira Browse this author | Tsutsui, Hiroyuki Browse this author →KAKEN DB | The JCARE-CARD Investigators Browse this author |
Keywords: | Atrial fibrillation | Heart failure | Mortality | Outcomes | Rehospitalization |
Issue Date: | 2009 |
Publisher: | The Japanese Circulation Society |
Journal Title: | Circulation Journal |
Volume: | 73 |
Issue: | 11 |
Start Page: | 2084 |
End Page: | 2090 |
Publisher DOI: | 10.1253/circj.CJ-09-0316 |
Abstract: | Background: Atrial fibrillation (AF) is a common arrhythmia in patients with heart failure (HF), but its prognostic importance is controversial. The effect of AF on long-term outcomes, including mortality and rehospitalization, among unselected HF patients hospitalized with HF in routine clinical practice in Japan was assessed in the present study. Methods and Results: The Japanese Cardiac Registry of Heart Failure in Cardiology (JCARE-CARD) prospectively studied the characteristics and treatment strategies of a broad sample of patients hospitalized with worsening HF and the outcomes were followed with an average of 2.4 years of follow-up. The study cohort (n=2,659) was grouped according to the presence (n=937; 35.2%) or absence (n=1,722; 64.8%) of AF at baseline. After multivariable adjustment, patients with and without AF had a comparable risk for all-cause death (adjusted hazard ratio (HR) 0.931, 95% confidence interval (CI) 0.690-1.258, P=0.643), cardiac death (adjusted HR 0.949, 95%CI 0.655-1.377, P=0.784), rehospitalization because of the worsening HF (adjusted HR 1.028, 95%CI 0.816-1.295, P=0.816), and all-cause death or rehospitalization (adjusted HR 1.039, 95%CI 0.842-1.281, P=0.722). Conclusions: Among patients hospitalized for HF in Japan, AF was common, but was not an independent risk for long-term adverse outcomes, including death or rehospitalization, in routine clinical practice. (Circ J 2009; 73: 2084-2090) |
Rights: | https://creativecommons.org/licenses/by-nc-nd/4.0/ |
Type: | article |
URI: | http://hdl.handle.net/2115/76965 |
Appears in Collections: | 北海道大学病院 (Hokkaido University Hospital) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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