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Characteristics and Outcomes of Hospitalized Patients With Heart Failure and Reduced vs Preserved Ejection Fraction
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| Title: | Characteristics and Outcomes of Hospitalized Patients With Heart Failure and Reduced vs Preserved Ejection Fraction |
| Authors: | Tsuchihashi-Makaya, Miyuki Browse this author | | Hamaguchi, Sanae Browse this author | | Kinugawa, Shintaro Browse this author →KAKEN DB | | Yokota, Takashi Browse this author →KAKEN DB | | Goto, Daisuke Browse this author | | Yokoshiki, Hisashi Browse this author →KAKEN DB | | Kato, Norihiro Browse this author | | Takeshita, Akira Browse this author | | Tsutsui, Hiroyuki Browse this author →KAKEN DB | | for the JCARE-CARD Investigators Browse this author |
| Keywords: | Ejection fraction | | Heart failure | | Mortality | | Outcome | | Rehospitalization |
| Issue Date: | 2009 |
| Journal Title: | Circulation Journal |
| Volume: | 73 |
| Issue: | 10 |
| Start Page: | 1893 |
| End Page: | 1900 |
| Publisher DOI: | 10.1253/circj.CJ-09-0254 |
| Abstract: | Background: Heart failure (HF) with preserved ejection fraction (EF) is common. We compared the characteristics, treatments, and outcomes in HF patients with reduced vs preserved EF by using the national registry database in Japan. Methods and Results: The Japanese Cardiac Registry of Heart Failure in Cardiology (JCARE-CARD) is a prospective observational study in a broad sample of patients hospitalized with worsening HF. The study enrolled 2,675 patients from 164 hospitals with an average of 2.4 years of follow-up. Patients with preserved EF (EF ?50% by echocardiography; n=429) were more likely to be older, female, have hypertension and atrial fibrillation, and less likely to have ischemic etiology compared with those with reduced EF (EF <40%; n=985). Unadjusted risk of in-hospital mortality (6.5% vs 3.9%; P=0.03) and post-discharge mortality (22.7% vs 17.8%; P=0.058) was slightly higher in patients with preserved EF, which, however, were not different after multivariable adjustment. Patients with preserved EF had similar rehospitalization rates (36.2% vs 33.4%; P=0.515) compared with patients with reduced EF. Conclusions: HF patients with preserved EF had a similar mortality risk and equally high rates of rehospitalization as those with reduced EF. Effective management strategies are critically needed to be established for this type of HF. (Circ J 2009; 73: 1893-1900) |
| Rights: | https://creativecommons.org/licenses/by-nc-nd/4.0/ |
| Type: | article |
| URI: | http://hdl.handle.net/2115/76966 |
| Appears in Collections: | 北海道大学病院 (Hokkaido University Hospital) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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