|
Hokkaido University Collection of Scholarly and Academic Papers >
Hokkaido University Hospital >
Peer-reviewed Journal Articles, etc >
Predictors of Long-Term Adverse Outcomes in Elderly Patients Over 80 Years Hospitalized With Heart Failure
This item is licensed under:Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
Title: | Predictors of Long-Term Adverse Outcomes in Elderly Patients Over 80 Years Hospitalized With Heart Failure |
Authors: | Hamaguchi, Sanae Browse this author | Kinugawa, Shintaro Browse this author →KAKEN DB | Goto, Daisuke Browse this author | Tsuchihashi-Makaya, Miyuki Browse this author | Yokota, Takashi Browse this author →KAKEN DB | Yamada, Satoshi Browse this author | Yokoshiki, Hisashi Browse this author →KAKEN DB | Takeshita, Akira Browse this author | Tsutsui, Hiroyuki Browse this author →KAKEN DB | JCARE-CARD Investigators Browse this author |
Keywords: | Elderly | Heart failure | Mortality | Outcomes | Prognosis |
Issue Date: | 2011 |
Publisher: | The Japanese Circulation Society |
Journal Title: | Circulation Journal |
Volume: | 75 |
Issue: | 10 |
Start Page: | 2403 |
End Page: | 2410 |
Publisher DOI: | 10.1253/circj.CJ-11-0267 |
Abstract: | Background: Aging is associated with adverse outcomes in patients with cardiac diseases. Whether elderly patients hospitalized with heart failure (HF) had increased risks for mortality and rehospitalization compared with younger patients during the long-term follow-up was examined. The predictors of these adverse outcomes were also identified. Methods and Results: The Japanese Cardiac Registry of Heart Failure in Cardiology (JCARE-CARD) studied prospectively the characteristics and treatments in a broad sample of 2,675 patients hospitalized with worsening HF and the outcomes were followed up. The majority of elderly patients were female, had lower body mass index (BMI), a higher rate of ischemic, valvular, and hypertensive heart disease as etiologies of HF, a lower estimated glomerular filtration rate (eGFR), lower hemoglobin, and higher left ventricular ejection fraction values. Even after adjustment for covariates, the elderly patients were associated with higher risks of adverse outcomes. The predictors for all-cause death were: lower eGFR, lower BMI, male sex, sustained ventricular tachycardia or fibrillation (VT/VF), and the use of diuretics at discharge. Conclusions: Among patients hospitalized with HF, elderly patients had a worse prognosis than younger patients. Lower eGFR, lower BMI, male sex, sustained VT/VF, and diuretic use were independent predictors for all-cause death in these patients with higher risk. (Circ J 2011; 75: 2403-2410) |
Rights: | https://creativecommons.org/licenses/by-nc-nd/4.0/ |
Type: | article |
URI: | http://hdl.handle.net/2115/76971 |
Appears in Collections: | 北海道大学病院 (Hokkaido University Hospital) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
|
|