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Iridium(I)-Catalyzed C-H Borylation in Air by Using Mechanochemistry
Title: | Iridium(I)-Catalyzed C-H Borylation in Air by Using Mechanochemistry |
Authors: | Pang, Yadong Browse this author | Ishiyama, Tatsuo Browse this author →KAKEN DB | Kubota, Koji Browse this author | Ito, Hajime Browse this author →KAKEN DB |
Keywords: | boron | C-H borylation | iridium | mechanochemistry | synthetic method |
Issue Date: | 27-Mar-2019 |
Publisher: | Wiley-Blackwell |
Journal Title: | Chemistry-A European journal |
Volume: | 25 |
Issue: | 18 |
Start Page: | 4654 |
End Page: | 4659 |
Publisher DOI: | 10.1002/chem.201900685 |
Abstract: | Mechanochemistry has been applied for the first time to an iridium(I)-catalyzed C-H borylation reaction. By using either none or just a catalytic amount of a liquid, the mechanochemical C-H borylation of a series of heteroaromatic compounds proceeded in air to afford the corresponding arylboronates in good-to-excellent yields. A one-pot mechanochemical C-H borylation/Suzuki-Miyaura cross-coupling sequence for the direct synthesis of 2-aryl indole derivatives is also described. The present study constitutes an important milestone towards the development of industrially attractive solvent-free C-H bond functionalization processes in air. |
Rights: | This is the peer reviewed version of the following article: Yadong Pang, Tatsuo Ishiyama, Koji Kubota, and Hajime Ito. Iridium(I)‐Catalyzed C−H Borylation in Air by Using Mechanochemistry. Chemistry: A European Journal. March 27 2019, 25(18), p. 4654 - 4659, which has been published in final form at https://doi.org/10.1002/chem.201900685 . This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. |
Type: | article (author version) |
URI: | http://hdl.handle.net/2115/77135 |
Appears in Collections: | 化学反応創成研究拠点:ICReDD (Institute for Chemical Reaction Design and Discovery : ICReDD) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 久保田 浩司
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