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Source localization in magnetoencephalography to identify epileptogenic foci.

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Title: Source localization in magnetoencephalography to identify epileptogenic foci.
Authors: Shiraishi, Hideaki Browse this author →KAKEN DB
Keywords: Magnetoencephalography
Single dipole method
Time–frequency analysis
Short-time Fourier transform analysis
Issue Date: Dec-2010
Publisher: Elsevier
Journal Title: Brain & development
Volume: 33
Issue: 3
Start Page: 276
End Page: 281
Publisher DOI: 10.1016/j.braindev.2010.10.019
PMID: 21075573
Abstract: Rationale: Magnetoencephalography (MEG) is useful to localize epileptic foci in epilepsy as MEG has higher spatio-temporalresolution than conventional diagnostic imaging studies; positron emission computed tomography, single photon emission com-puted tomography and magnetic resonance imaging (MRI).Methods: We use 204-channel helmet-shaped MEG with a sampling rate of 600 Hz. A single dipole method calculates equivalentcurrent dipoles to localize epileptic sources. The equivalent current dipoles are superimposed onto MRI as magnetic source imaging(MSI). Ictal MEG data are analyzed using time?frequency analysis. The power spectrum density is calculated using short-timeFourier transform and superimposed onto MRI results.Results:Clustered equivalent current dipoles represent epileptogenic zones in patients with localization-related epilepsy. The sur-gical plan is reliably developed from source localizations of dipoles and power spectrum of interictal spike discharges, and ictalfrequency.Conclusion: MEG is indispensable in diagnosis and surgical resection for epilepsy to accurately localize the epileptogenic zone.
Rights: © 2010. This manuscript version is made available under the CC-BY-NC-ND 4.0 license
Type: article (author version)
Appears in Collections:北海道大学病院 (Hokkaido University Hospital) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 白石 秀明

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