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Indoor environmental pollutants and their association with sick house syndrome among adults and children in elementary school

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Title: Indoor environmental pollutants and their association with sick house syndrome among adults and children in elementary school
Authors: Kishi, Reiko Browse this author →KAKEN DB
Ketema, Rahel Mesfin Browse this author
Ait Bamai, Yu Browse this author
Araki, Atsuko Browse this author →KAKEN DB
Kawai, Toshio Browse this author
Tsuboi, Tazuru Browse this author
Saito, Ikue Browse this author
Yoshioka, Eiji Browse this author →KAKEN DB
Saito, Takeshi Browse this author →KAKEN DB
Keywords: Sick house syndrome
Indoor chemicals
Biological factors
Dampness
Dwelling
Issue Date: 15-May-2018
Publisher: Elsevier
Journal Title: Building and environment
Volume: 136
Start Page: 293
End Page: 301
Publisher DOI: 10.1016/j.buildenv.2018.03.056
Abstract: Sick house syndrome (SHS) derived from sick building syndrome (SBS) is used to describe symptoms that inhabitants experience due to indoor environment and personal factors, and children might be more susceptible to the effects of SHS than adults. However, there have been no comprehensive studies on effects of indoor pollutants exposure in relation to SHS. Thus, the aim of this study is to examine the association between indoor pollutants and SHS in children and adults who live in the same dwelling. This is a cross-sectional study on 184 elementary school children and 273 adults/adolescents in Sapporo, Japan. Indoor pollutants were measured in air and dust collected from 128 dwellings. Results showed children (20.6%) have higher prevalence of any symptoms than adults/adolescents (15.1%). Among SHS, mucosal symptoms were the most common in both children and adults/adolescents. Doctor diagnosed allergies, building age, dampness, and ventilation system showed significant association with prevalence of SHS. Formaldehyde, di(isobutyl) phthalate (DiBP), di(2-ethylhexyl) phthalate (DEHP), di(isononyl) phthalate (DiNP), endotoxin, and 13-glucan were detected in all dwellings. Any symptoms and mucosal symptoms were significantly associated with the exposure to 2-ethyl-1-hexanol (2E1H). Floor dust DiNP, multi-surface dust Tris(2-butoxyethyl) phosphate with mucosal symptoms and endotoxin with dermal symptoms were inversely associated in adults/adolescent. Multi-surface dust DiBP also showed inverse association with mucosal symptoms in children. 2E1H emission increased with dampness in the dwellings thus, eliminating dampness in the dwellings may reduce the emissions of 2E1H and the risk of SHS in residents.
Rights: © 2018. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
http://creativecommons.org/licenses/by-nc-nd/4.0/
Type: article (author version)
URI: http://hdl.handle.net/2115/78011
Appears in Collections:環境健康科学研究教育センター (Center for Environmental and Health Sciences) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 岸 玲子

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