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Hokkaido University Collection of Scholarly and Academic Papers >
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Mechanical properties of a new thermally deformable mitral valve annuloplasty ring and its effects on the mitral valve
| Title: | Mechanical properties of a new thermally deformable mitral valve annuloplasty ring and its effects on the mitral valve |
| Authors: | Seki, Tatsuya Browse this author | | Jimuro, Katsuyoshi Browse this author | | Shingu, Yasushige Browse this author | | Wakasa, Satoru Browse this author →KAKEN DB | | Katoh, Hiroki Browse this author | | Ooka, Tomonori Browse this author →KAKEN DB | | Tachibana, Tsuyoshi Browse this author | | Kubota, Suguru Browse this author →KAKEN DB | | Ohashi, Toshiro Browse this author →KAKEN DB | | Matsui, Yoshiro Browse this author →KAKEN DB |
| Keywords: | Mitral valve | | Mitral valve annuloplasty ring | | Polycaprolactone |
| Issue Date: | Jun-2019 |
| Publisher: | Springer |
| Journal Title: | Journal of artificial organs |
| Volume: | 22 |
| Issue: | 2 |
| Start Page: | 126 |
| End Page: | 133 |
| Publisher DOI: | 10.1007/s10047-018-1084-8 |
| PMID: | 30456661 |
| Abstract: | Ideally, an annuloplasty ring's shape should be changed intraoperatively if mitral valve repair is unsuccessful because of a short coaptation length or systolic anterior motion. Several post-implantation adjustable rings have been developed, but they are not freely deformable and are unsuitable for asymmetric repair of the valvular annulus. We developed a novel thermally deformable mitral annuloplasty ring to address these problems and assessed the ring's mechanical properties and its effect on the mitral valve anatomy. This ring was made of polycaprolactone. Tensile and bending tests were performed to evaluate the ring's mechanical properties. The ratio of the transverse and septal-lateral length was determined as 4:3. Using 10 pig hearts, we measured the post-deformation coaptation length and minimum distance from the coaptation to the ventricular septum, which is a factor of abnormal systolic anterior motion of the mitral valve. In the mechanical tests, the ring's yield point was greater than the deformation force of the annulus in humans. In pigs with deformation from 4:3 to 4:2, the coaptation length was significantly increased in each mitral valve part. In pigs with deformation from 4:3 to 4:4, the minimum distance from the coaptation to the ventricular septum was significantly increased. Asymmetrical ring deformation increased the coaptation length only at the deformed area. In conclusion, this new thermally deformable mitral annuloplasty ring could be order-made to effectively change the coaptation length in all parts of the mitral valve and the distance from the coaptation to septum post-deformation via intraoperative heating. |
| Rights: | The final publication is available at link.springer.com. |
| Type: | article (author version) |
| URI: | http://hdl.handle.net/2115/78253 |
| Appears in Collections: | 医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 新宮 康栄
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