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Mechanical properties of a new thermally deformable mitral valve annuloplasty ring and its effects on the mitral valve

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Please use this identifier to cite or link to this item:http://hdl.handle.net/2115/78253

Title: Mechanical properties of a new thermally deformable mitral valve annuloplasty ring and its effects on the mitral valve
Authors: Seki, Tatsuya Browse this author
Jimuro, Katsuyoshi Browse this author
Shingu, Yasushige Browse this author
Wakasa, Satoru Browse this author →KAKEN DB
Katoh, Hiroki Browse this author
Ooka, Tomonori Browse this author →KAKEN DB
Tachibana, Tsuyoshi Browse this author
Kubota, Suguru Browse this author →KAKEN DB
Ohashi, Toshiro Browse this author →KAKEN DB
Matsui, Yoshiro Browse this author →KAKEN DB
Keywords: Mitral valve
Mitral valve annuloplasty ring
Polycaprolactone
Issue Date: Jun-2019
Publisher: Springer
Journal Title: Journal of artificial organs
Volume: 22
Issue: 2
Start Page: 126
End Page: 133
Publisher DOI: 10.1007/s10047-018-1084-8
PMID: 30456661
Abstract: Ideally, an annuloplasty ring's shape should be changed intraoperatively if mitral valve repair is unsuccessful because of a short coaptation length or systolic anterior motion. Several post-implantation adjustable rings have been developed, but they are not freely deformable and are unsuitable for asymmetric repair of the valvular annulus. We developed a novel thermally deformable mitral annuloplasty ring to address these problems and assessed the ring's mechanical properties and its effect on the mitral valve anatomy. This ring was made of polycaprolactone. Tensile and bending tests were performed to evaluate the ring's mechanical properties. The ratio of the transverse and septal-lateral length was determined as 4:3. Using 10 pig hearts, we measured the post-deformation coaptation length and minimum distance from the coaptation to the ventricular septum, which is a factor of abnormal systolic anterior motion of the mitral valve. In the mechanical tests, the ring's yield point was greater than the deformation force of the annulus in humans. In pigs with deformation from 4:3 to 4:2, the coaptation length was significantly increased in each mitral valve part. In pigs with deformation from 4:3 to 4:4, the minimum distance from the coaptation to the ventricular septum was significantly increased. Asymmetrical ring deformation increased the coaptation length only at the deformed area. In conclusion, this new thermally deformable mitral annuloplasty ring could be order-made to effectively change the coaptation length in all parts of the mitral valve and the distance from the coaptation to septum post-deformation via intraoperative heating.
Rights: The final publication is available at link.springer.com.
Type: article (author version)
URI: http://hdl.handle.net/2115/78253
Appears in Collections:医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 新宮 康栄

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