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Reversible splenial lesion in new-onset refractory status epilepticus : A case report

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Title: Reversible splenial lesion in new-onset refractory status epilepticus : A case report
Authors: Eguchi, Katsuki Browse this author
Tsuzaka, Kazufumi Browse this author
Yabe, Ichiro Browse this author →KAKEN DB
Sasaki, Hidenao Browse this author →KAKEN DB
Keywords: New-onset refractory status epilepticus
Reversible splenial lesion
Issue Date: Aug-2019
Publisher: Elsevier
Journal Title: Clinical neurology and neurosurgery
Volume: 183
Start Page: 105392
Publisher DOI: 10.1016/j.clineuro.2019.105392
PMID: 31254907
Abstract: A 33-year-old man developed a generalized tonic-clonic seizure after a week of fever and fatigue. Diffusion weighted and fluid attenuated inversion recovery magnetic resonance imaging showed a hyperintense lesion in the splenium of the corpus callosum, and the lesion disappeared within a few days. The patient developed refractory status epilepticus despite treatment with multiple antiepileptic drugs. After concurrent administration of high-dose methylprednisolone, intravenous immunoglobulin, intravenous anesthetics and antiepileptic drugs, the patient achieved complete suppression of seizures. To the best of our knowledge, this is the first case of a new-onset refractory status epilepticus with a reversible splenial lesion.
Rights: ©2019. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
http://creativecommons.org/licenses/by-nc-nd/4.0/
Type: article (author version)
URI: http://hdl.handle.net/2115/79021
Appears in Collections:医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 矢部 一郎

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