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Does Subjective Cognitive Function Mediate the Effect of Affective Temperaments on Functional Disability in Japanese Adults?
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| Title: | Does Subjective Cognitive Function Mediate the Effect of Affective Temperaments on Functional Disability in Japanese Adults? |
| Authors: | Toyoshima, Kuniyoshi Browse this author →KAKEN DB | | Inoue, Takeshi Browse this author →KAKEN DB | | Masuya, Jiro Browse this author | | Fujimura, Yota Browse this author | | Higashi, Shinji Browse this author | | Kusumi, Ichiro Browse this author →KAKEN DB |
| Keywords: | cognition | | depression | | adult | | Sheehan Disability Scale | | TEMPS-A | | subjective cognitive dysfunction |
| Issue Date: | 8-Jul-2020 |
| Publisher: | Dove Medical Press |
| Journal Title: | Neuropsychiatric Disease and Treatment |
| Volume: | 16 |
| Start Page: | 1675 |
| End Page: | 1684 |
| Publisher DOI: | 10.2147/NDT.S256647 |
| Abstract: | Purpose: Functional disability is affected by subjective cognitive function, depressive symptoms, and affective temperaments in adults. However, the role of subjective cognitive function as a mediator of affective temperaments in functional disability remains unknown. Therefore, we aimed to determine how subjective cognitive function mediates the effect of affective temperaments on functional disability in adults. Materials and Methods: A total of 544 participants completed the Temperament Evaluation of Memphis, Pisa, Paris, and San Diego-Auto questionnaire version (TEMPS-A), the Patient Health Questionnaire-9 (PHQ-9), the cognitive complaints in bipolar disorder rating assessment (COBRA), and the Sheehan Disability Scale (SDS). The association among these instruments was evaluated by multiple regression and covariance structure analyses. Results: The structural equation model showed that the COBRA scores could be predicted directly by the four affective temperaments of the TEMPS-A (cyclothymic, depressive, irritable, and anxious) and indirectly by the PHQ-9. Moreover, the SDS score was predicted directly by these four affective temperaments and indirectly by the COBRA and PHQ-9. Conclusion: Subjective cognitive function mediates the effect of affective temperaments on functional disability in Japanese adults. However, the cross-sectional design may limit the identification of causal associations between the parameters. In the present study, the participants were from a specific community population; therefore, the results may not be generalizable to other communities. |
| Rights: | http://creativecommons.org/licenses/by-nc/3.0/ |
| Type: | article |
| URI: | http://hdl.handle.net/2115/79078 |
| Appears in Collections: | 医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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