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Percutaneous insertion of hepatic fiducial true-spherical markers for real-time adaptive radiotherapy

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Please use this identifier to cite or link to this item:http://hdl.handle.net/2115/79242

Title: Percutaneous insertion of hepatic fiducial true-spherical markers for real-time adaptive radiotherapy
Authors: Morita, Ryo Browse this author
Abo, Daisuke Browse this author →KAKEN DB
Sakuhara, Yusuke Browse this author →KAKEN DB
Soyama, Takeshi Browse this author →KAKEN DB
Katoh, Norio Browse this author →KAKEN DB
Miyamoto, Naoki Browse this author →KAKEN DB
Uchinami, Yuusuke Browse this author
Shimizu, Shinichi Browse this author →KAKEN DB
Shirato, Hiroki Browse this author →KAKEN DB
Kudo, Kohsuke Browse this author →KAKEN DB
Keywords: Fiducial marker
Percutaneous transhepatic implantation
Radiation therapy
True-spherical marker
Issue Date: 13-Sep-2019
Publisher: Taylor & Francis
Journal Title: Minimally invasive therapy and allied technologies
Publisher DOI: 10.1080/13645706.2019.1663217
PMID: 31516050
Abstract: Purpose: This study evaluated the success rate and complications of percutaneous implantation of hepatic fiducial true-spherical gold markers for real-time adaptive radiotherapy (RAR), which constitutes real-time image-guided radiotherapy with gating. Material and methods: We retrospectively evaluated 100 patients who underwent 116 percutaneous intrahepatic implantations of 2-mm-diameter, spherical, gold fiducial markers before RAR from 1999 to 2016, with Seldinger's method. We defined technical success as marker placement at the intended liver parenchyma, without mispositioning, and clinical success as successful tracking of the gold marker and completion of planned RAR. Complications related to marker placement were assessed. Results: The technical success rate for true-spherical gold marker implantation was 92.2% (107/116). Nine of 116 markers migrated (intra-procedurally in seven patients, delayed in two patients). Migration out of the liver (n = 4) or intrahepatic vessels (n = 5) occurred without complications; these markers were not retrieved. The clinical success rate was 100.0% (115/115). Abdominal pain occurred in 16 patients, fever and hemorrhage in seven patients each, and pneumothorax and nausea in one patient each. No major complications were encountered. Conclusions: Percutaneous transhepatic implantation of true-spherical gold markers for RAR is feasible and can be conducted with a high success rate and low complication rate.
Rights: This is an Accepted Manuscript of an article published by Taylor & Francis in Minimally Invasive Therapy & Allied Technologies on 13 Sep 2019, available online: http://www.tandfonline.com/10.1080/13645706.2019.1663217.
Type: article (author version)
URI: http://hdl.handle.net/2115/79242
Appears in Collections:国際連携研究教育局 : GI-CoRE (Global Institution for Collaborative Research and Education : GI-CoRE) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 阿保 大介

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