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Risk factors for residual mitral regurgitation after aortic valve replacement in patients with severe aortic valve stenosis and moderate mitral regurgitation

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Please use this identifier to cite or link to this item:http://hdl.handle.net/2115/79360

Title: Risk factors for residual mitral regurgitation after aortic valve replacement in patients with severe aortic valve stenosis and moderate mitral regurgitation
Authors: Shingu, Yasushige Browse this author →KAKEN DB
Iwano, Hiroyuki Browse this author →KAKEN DB
Murakami, Tatsuya Browse this author
Katoh, Nobuyasu Browse this author
Ooka, Tomonori Browse this author →KAKEN DB
Katoh, Hiroki Browse this author
Kubota, Suguru Browse this author →KAKEN DB
Matsui, Yoshiro Browse this author →KAKEN DB
Keywords: Aortic valve stenosis
Mitral regurgitation
Issue Date: Oct-2019
Publisher: Springer
Journal Title: General thoracic and cardiovascular surgery
Volume: 67
Start Page: 849
End Page: 854
Publisher DOI: 10.1007/s11748-019-01110-w
Abstract: Objectives While it was reported that patients with residual moderate mitral regurgitation (MR) after surgical aortic valve replacement (SAVR) had a poorer prognosis than those without it, the risk factors for residual MR have not been fully elucidated. The aim of the study was to evaluate risk factors for residual MR after SAVR. Methods Of the 222 patients who underwent isolated SAVR from 2001 to 2018, 33 (11 men; age: 74 +/- 7 years) had functional moderate MR before surgery. The risk factors for residual MR were evaluated by comparing patients with residual moderate MR (n = 11, 33%) with those who exhibited improved post-surgery MR (n = 22, 67%). Results The left atrial diameter was significantly larger in the residual MR group (51 +/- 7 mm) than in the improved MR group (46 +/- 5 mm; P = 0.049). The mean pressure gradient at the aortic valve was significantly smaller in the residual MR group (52 +/- 18 mmHg) than in the improved MR group (69 +/- 22 mmHg; P = 0.043). A ratio of left atrial diameter (mm) and mean aortic valve pressure gradient (mmHg) greater than 0.9 predicted residual MR with a sensitivity of 70% and a specificity of 74% (area under the ROC curve: 0.779; P = 0.015). Conclusions In patients with severe aortic valve stenosis and moderate MR, a high ratio of preoperative left atrial diameter and mean aortic valve pressure gradient would be a parameter predicting residual moderate MR post-SAVR.
Rights: This is a post-peer-review, pre-copyedit version of an article published in General thoracic and cardiovascular surgery. The final authenticated version is available online at: https://doi.org/10.1007/s11748-019-01110-w
Type: article (author version)
URI: http://hdl.handle.net/2115/79360
Appears in Collections:医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 新宮 康栄

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