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The SIRS criteria have better performance for predicting infection than qSOFA scores in the emergency department

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Title: The SIRS criteria have better performance for predicting infection than qSOFA scores in the emergency department
Authors: Gando, Satoshi Browse this author →KAKEN DB
Shiraishi, Atsushi Browse this author →KAKEN DB
Abe, Toshikazu Browse this author →KAKEN DB
Kushimoto, Shigeki Browse this author →KAKEN DB
Mayumi, Toshihiko Browse this author →KAKEN DB
Fujishima, Seitaro Browse this author →KAKEN DB
Hagiwara, Akiyoshi Browse this author
Shiino, Yasukazu Browse this author
Shiraishi, Shin-ichiro Browse this author →KAKEN DB
Hifumi, Toru Browse this author
Otomo, Yasuhiro Browse this author →KAKEN DB
Okamoto, Kohji Browse this author
Sasaki, Junichi Browse this author →KAKEN DB
Takuma, Kiyotsugu Browse this author →KAKEN DB
Yamakawa, Kazuma Browse this author →KAKEN DB
Issue Date: 15-May-2020
Publisher: Nature Publishing Group
Journal Title: Scientific reports
Volume: 10
Issue: 1
Start Page: 8095
Publisher DOI: 10.1038/s41598-020-64314-8
Abstract: Systemic inflammatory response syndrome (SIRS) reportedly has a low performance for distinguishing infection from non-infection. We explored the distribution of the patients diagnosed by SIRS (SIRS patients) or a quick sequential organ failure assessment (qSOFA) (qSOFA patients) and confirmed the performance of the both for predicting ultimate infection after hospital admission. We retrospectively analyzed the data from a multicenter prospective study. When emergency physicians suspected infection, SIRS or the qSOFA were applied. The area under the receiver operating characteristic curves (AUC) was used to assess the performance of the SIRS and qSOFA for predicting established infection. A total of 1,045 patients were eligible for this study. The SIRS patients accounted for 91.6% of qSOFA patients and they showed a higher rate of final infection than that of non-SIRS patients irrespective of the qSOFA diagnosis. The AUCs for predicting infection with SIRS and a qSOFA were 0.647 and 0.582, respectively. The SIRS significantly predicted an ultimate infection (AUC, 0.675; p=0.018) in patients who met the SIRS and qSOFA simultaneously. In conclusion, the SIRS patients included almost all qSOFA patients. SIRS showed a better performance for predicting infection for qSOFA in those who met both definitions.
Rights: http://creativecommons.org/licenses/by/4.0/
Type: article
URI: http://hdl.handle.net/2115/79481
Appears in Collections:医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

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