Hokkaido University Collection of Scholarly and Academic Papers >
Graduate School of Medicine / Faculty of Medicine >
Peer-reviewed Journal Articles, etc >
Green tea consumption and risk of hematologic neoplasms : the Japan Collaborative Cohort Study for Evaluation of Cancer Risk (JACC Study)
Title: | Green tea consumption and risk of hematologic neoplasms : the Japan Collaborative Cohort Study for Evaluation of Cancer Risk (JACC Study) |
Authors: | Takada, Midori Browse this author | Yamagishi, Kazumasa Browse this author →KAKEN DB | Iso, Hiroyasu Browse this author →KAKEN DB | Tamakoshi, Akiko Browse this author →KAKEN DB |
Keywords: | Epigallocatechin-3-gallate | Hematologic neoplasm | Japan collaborative cohort study for evaluation of cancer risk | Preventive medicine | Green tea | Acute myeloid leukemia |
Issue Date: | Nov-2019 |
Publisher: | Springer |
Journal Title: | Cancer causes & control |
Volume: | 30 |
Issue: | 11 |
Start Page: | 1223 |
End Page: | 1230 |
Publisher DOI: | 10.1007/s10552-019-01220-z |
Abstract: | Purpose Experimental studies suggested that green tea may have an anticancer effect on hematologic neoplasms. However, few prospective studies have been conducted. Methods A total of 65,042 individuals aged 40-79 years participated in this study and completed a self-administered questionnaire about their lifestyle and medical history at baseline (1988-1990). Of these, 52,462 individuals living in 24 communities with information on incident hematologic neoplasms available in the cancer registry, who did not have a history of cancer and provided valid information on frequency of green tea consumption, were followed through 2009. Hazard ratios (HRs) and 95% confidence intervals (CIs) for the incidence of hematologic neoplasms according to green tea consumption were analyzed. Results The incidence of hematologic neoplasms during a median follow-up of 13.3 years was 323. Compared with the never-drinkers of green tea, the multivariate HRs and 95% CIs for total hematologic neoplasms in green tea drinkers of = 2 cups/day, 3-4 cups/day, and = 5 cups/day were 0.65 (0.42-1.00), 0.73 (0.47-1.13), and 0.63 (0.42-0.96), respectively. The association was more prominent for acute myeloid leukemias and follicular lymphomas. Conclusions The present cohort study suggests a protective effect of green tea against hematologic neoplasms, especially acute myeloid leukemias. |
Rights: | This is a post-peer-review, pre-copyedit version of an article published in Cancer Causes & Control. The final authenticated version is available online at: http://dx.doi.org/10.1007/s10552-019-01220-z |
Type: | article (author version) |
URI: | http://hdl.handle.net/2115/79654 |
Appears in Collections: | 医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
|
Submitter: 玉腰 暁子
|