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Association of tea consumption and the risk of gastric cancer in Japanese adults : the Japan Collaborative Cohort Study

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Title: Association of tea consumption and the risk of gastric cancer in Japanese adults : the Japan Collaborative Cohort Study
Authors: Sheerah, Haytham Browse this author
Keyang, Liu Browse this author
Eshak, Ehab Salah Browse this author →KAKEN DB
Cui, Renzhe Browse this author →KAKEN DB
Shirai, Kokoro Browse this author →KAKEN DB
Muraki, Isao Browse this author →KAKEN DB
Iso, Hiroyasu Browse this author →KAKEN DB
Tamakoshi, Akiko Browse this author →KAKEN DB
Keywords: total tea
green tea
black tea
oolong tea
gastric cancer
Issue Date: 2020
Publisher: BMJ Publishing Group
Journal Title: BMJ Open
Volume: 10
Issue: 10
Start Page: e038243
Publisher DOI: 10.1136/bmjopen-2020-038243
Abstract: Objective To examine the possible relationship between tea consumption and risk of gastric cancer (GC) among Japanese men and women included in a large Japanese population-based study titled the Japan Collaborative Cohort (JACC) Study. Design Prospective cohort study. Setting A population-based cohort included subjects who were recruited from 24 areas of JACC Study, in which data regarding the incidence of cancer were available. Participants 63 848 participants (26 025 men and 37 823 women), aged 40-79, were included in the analyses and underwent follow-up (median 13.3 years) prospectively in research on cancer incidence. Primary and secondary outcome measures The primary outcome variable was the risk of GC according to the frequency intakes of total tea, green tea, black tea and oolong tea. The adjusted HRs for the risk of GC associated with tea consumption were calculated using the Cox proportional hazards model. Results 1494 cases of GC were detected (960 men and 534 women) during the follow-up period. The multivariable-adjusted HRs for the risk of GC in the highest versus lowest quintiles of total tea intake were 1.05 (0.83-1.33); p trend=0.50 in men, and 0.82 (0.60-1.12); p trend=0.45 in women. There was no association found between the consumption of green tea, black tea or oolong tea with the risk for GC in either gender. Conclusions In this large community-based prospective cohort study, tea consumption was not associated with the risk of GC in either gender.
Type: article
Appears in Collections:医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

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