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Impact of a Rice-Centered Diet on the Quality of Sleep in Association with Reduced Oxidative Stress : A Randomized, Open, Parallel-Group Clinical Trial
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| Title: | Impact of a Rice-Centered Diet on the Quality of Sleep in Association with Reduced Oxidative Stress : A Randomized, Open, Parallel-Group Clinical Trial |
| Authors: | Koga, Minori Browse this author →KAKEN DB | | Toyomaki, Atsuhito Browse this author →KAKEN DB | | Kiso, Yoshinobu Browse this author | | Kusumi, Ichiro Browse this author →KAKEN DB |
| Keywords: | rice-centered diet | | sleep quality | | metabolome | | oxidative stress |
| Issue Date: | Oct-2020 |
| Publisher: | MDPI |
| Journal Title: | Nutrients |
| Volume: | 12 |
| Issue: | 10 |
| Start Page: | 2926 |
| Publisher DOI: | 10.3390/nu12102926 |
| Abstract: | Previously, we found that a Japanese diet was associated with psychological status, and a combination of rice and miso was related to mental and physical health. We hypothesized that the intake of a rice-based diet affected mental and physical health and aimed to investigate the consequences of a dietary intervention with rice. We conducted a randomized, open-label, parallel-group clinical trial that included 60 participants, who were randomly assigned to receive either rice-based meals or meals with other cereals for three daily meals over 2 months. The participants were surveyed for psychological status and biochemical changes. Sleep quality index scores showed significant improvement after the rice-based intervention. Additionally, blood oxidative stress levels were reduced in the rice-diet group compared with the no-rice-diet group. Although the molecular mechanisms should be investigated in detail, our findings suggest that controlling oxidative stress through the intake of a rice-centered diet may be key to improving sleep quality. |
| Rights: | https://creativecommons.org/licenses/by/4.0/ |
| Type: | article |
| URI: | http://hdl.handle.net/2115/80001 |
| Appears in Collections: | 医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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