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Impact of a Rice-Centered Diet on the Quality of Sleep in Association with Reduced Oxidative Stress : A Randomized, Open, Parallel-Group Clinical Trial

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Title: Impact of a Rice-Centered Diet on the Quality of Sleep in Association with Reduced Oxidative Stress : A Randomized, Open, Parallel-Group Clinical Trial
Authors: Koga, Minori Browse this author →KAKEN DB
Toyomaki, Atsuhito Browse this author →KAKEN DB
Kiso, Yoshinobu Browse this author
Kusumi, Ichiro Browse this author →KAKEN DB
Keywords: rice-centered diet
sleep quality
metabolome
oxidative stress
Issue Date: Oct-2020
Publisher: MDPI
Journal Title: Nutrients
Volume: 12
Issue: 10
Start Page: 2926
Publisher DOI: 10.3390/nu12102926
Abstract: Previously, we found that a Japanese diet was associated with psychological status, and a combination of rice and miso was related to mental and physical health. We hypothesized that the intake of a rice-based diet affected mental and physical health and aimed to investigate the consequences of a dietary intervention with rice. We conducted a randomized, open-label, parallel-group clinical trial that included 60 participants, who were randomly assigned to receive either rice-based meals or meals with other cereals for three daily meals over 2 months. The participants were surveyed for psychological status and biochemical changes. Sleep quality index scores showed significant improvement after the rice-based intervention. Additionally, blood oxidative stress levels were reduced in the rice-diet group compared with the no-rice-diet group. Although the molecular mechanisms should be investigated in detail, our findings suggest that controlling oxidative stress through the intake of a rice-centered diet may be key to improving sleep quality.
Rights: https://creativecommons.org/licenses/by/4.0/
Type: article
URI: http://hdl.handle.net/2115/80001
Appears in Collections:医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

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