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Retroperitoneal extragonadal germ cell tumor without distant metastasis : a case report

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Title: Retroperitoneal extragonadal germ cell tumor without distant metastasis : a case report
Authors: Furumido, Jun Browse this author
Osawa, Takahiro Browse this author →KAKEN DB
Kikuchi, Hiroshi Browse this author →KAKEN DB
Matsumoto, Ryuji Browse this author →KAKEN DB
Abe, Takashige Browse this author →KAKEN DB
Takakuwa, Emi Browse this author →KAKEN DB
Shinohara, Nobuo Browse this author →KAKEN DB
Keywords: Mortality
Radical cystectomy
Issue Date: Jan-2020
Publisher: Springer
Journal Title: International Cancer Conference Journal
Volume: 9
Issue: 1
Start Page: 5
End Page: 8
Publisher DOI: 10.1007/s13691-019-00384-4
Abstract: A 66-year-old man was referred to our hospital for an incidentally detected 40-mm mass located at the inter-aortocaval area around the renal hilum. Positron emission tomography CT revealed high accumulation (SUVmax 12.382) without distant metastasis. Bilateral testes were normal by ultrasonography and physical examination, but the serum AFP level was increased to 1161 ng/mL. The pathology based on trans-duodenal needle biopsy demonstrated a yolk sac tumor; therefore, we diagnosed him with retroperitoneal primary germ cell tumor. Due to old age, the potential toxicity of systemic chemotherapy, and no significant signs of invasion to adjacent organs, we performed surgical resection. Although the AFP level decreased to 13.2 ng/mL postoperatively, it increased to 553 ng/mL 2 months after surgery without clinical recurrence on imaging studies. Four cycles of a VIP regimen (VP-16, ifosfamide, and CDDP) were performed, and the AFP level normalized to 2.4 ng/mL. The patient is now disease-free 1 year and 6 months after surgery.
Rights: This is a post-peer-review, pre-copyedit version of an article published in International Cancer Conference Journal. The final authenticated version is available online at:
Type: article (author version)
Appears in Collections:北海道大学病院 (Hokkaido University Hospital) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 大澤 崇宏

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