| Title: | Long-term outcomes and risk factors of recurrent biliary obstruction after permanent endoscopic biliary stenting for choledocholithiasis in high-risk patients |
| Authors: | Sugiura, Ryo Browse this author |
| Naruse, Hirohito Browse this author |
| Yamato, Hiroaki Browse this author |
| Kudo, Taiki Browse this author |
| Yamamoto, Yoshiya Browse this author |
| Hatanaka, Kazuteru Browse this author |
| Ito, Jun Browse this author |
| Kinoshita, Kenji Browse this author |
| Miyamoto, Shuichi Browse this author |
| Higashino, Masayuki Browse this author |
| Hayasaka, Shuhei Browse this author |
| Sakamoto, Naoya Browse this author →KAKEN DB |
| Keywords: | common bile duct stone |
| endoscopic biliary stenting |
| long-term outcome |
| permanent endoscopic biliary stenting |
| recurrent biliary obstruction |
| Issue Date: | Apr-2020 |
| Publisher: | John Wiley & Sons |
| Journal Title: | Journal of Digestive Disease |
| Volume: | 21 |
| Issue: | 4 |
| Start Page: | 246 |
| End Page: | 251 |
| Publisher DOI: | 10.1111/1751-2980.12859 |
| Abstract: | Objective To elucidate the long-term outcomes of permanent endoscopic biliary stenting (EBS) and risk factors for recurrent biliary obstruction (RBO) in high-risk or elderly patients with common bile duct (CBD) stones. Methods The electronic database of Hakodate Municipal Hospital was searched to identify elderly or high-risk patients with CBD stones who had undergone permanent EBS using a plastic stent without stone removal and were followed up between April 2011 and May 2019, with no further intervention until symptoms occurred. Results We analyzed a total of 47 patients, of whom 19 (40.4%) were men, with a median age of 86 years (interquartile range 80-90 years). RBO and death without biliary disease occurred in 14 (29.8%) and 19 (40.4%) patients, respectively. The cumulative RBO rates at 20, 40, and 60 months were 22.1%, 31.8%, and 35.5%, respectively. The median time to RBO was 13.0 and 38.0 months in the group with CBD stone >= 15 mm and 11-14 mm in diameter, respectively. The cumulative RBO incidence rate in the group with CBD stone <= 10 mm in diameter did not reach 50%. The cumulative RBO incidence rates were significantly different among the three groups based on the CBD stone diameter (competing risk analysis, P < 0.01). Multivariate analysis showed that an increase in CBD stone diameter predicted the increased risk of RBO (hazard ratio 1.26, P = 0.01). Conclusions Permanent EBS is a feasible option for high-risk patients with small CBD stones. |
| Rights: | This is the peer reviewed version of the following article: Sugiura, R, Naruse, H, Yamato, H, et al. Long‐term outcomes and risk factors of recurrent biliary obstruction after permanent endoscopic biliary stenting for choledocholithiasis in high‐risk patients. J Dig Dis. 2020; 21: 246-251, which has been published in final form at https://doi.org/10.1111/1751-2980.12859. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. |
| Type: | article (author version) |
| URI: | http://hdl.handle.net/2115/80854 |
| Appears in Collections: | 医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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