| Title: | Anthropogenic interferences lead to gut microbiome dysbiosis in Asian elephants and may alter adaptation processes to surrounding environments |
| Authors: | Moustafa, Mohamed Abdallah Mohamed Browse this author |
| Chel, Hla Myet Browse this author |
| Thu, May June Browse this author |
| Bawm, Saw Browse this author |
| Htun, Lat Lat Browse this author |
| Win, Mar Mar Browse this author |
| Oo, Zaw Min Browse this author |
| Ohsawa, Natsuo Browse this author |
| Lahdenpera, Mirkka Browse this author |
| Mohamed, Wessam Mohamed Ahmed Browse this author |
| Ito, Kimihito Browse this author →KAKEN DB |
| Nonaka, Nariaki Browse this author →KAKEN DB |
| Nakao, Ryo Browse this author →KAKEN DB |
| Katakura, Ken Browse this author →KAKEN DB |
| Issue Date: | 12-Jan-2021 |
| Publisher: | Nature Research |
| Journal Title: | Scientific reports |
| Volume: | 11 |
| Issue: | 1 |
| Start Page: | 741 |
| Publisher DOI: | 10.1038/s41598-020-80537-1 |
| Abstract: | Human activities interfere with wild animals and lead to the loss of many animal populations. Therefore, efforts have been made to understand how wildlife can rebound from anthropogenic disturbances. An essential mechanism to adapt to environmental and social changes is the fluctuations in the host gut microbiome. Here we give a comprehensive description of anthropogenically induced microbiome alterations in Asian elephants (n=30). We detected gut microbial changes due to overseas translocation, captivity and deworming. We found that microbes belonging to Planococcaceae had the highest contribution in the microbiome alterations after translocation, while Clostridiaceae, Spirochaetaceae and Bacteroidia were the most affected after captivity. However, deworming significantly changed the abundance of Flavobacteriaceae, Sphingobacteriaceae, Xanthomonadaceae, Weeksellaceae and Burkholderiaceae. These findings may provide fundamental ideas to help guide the preservation tactics and probiotic replacement therapies of a dysbiosed gut microbiome in Asian elephants. More generally, these results show the severity of anthropogenic activities at the level of gut microbiome, altering the adaptation processes to new environments and the subsequent capability to maintain normal physiological processes in animals. |
| Rights: | http://creativecommons.org/licenses/by/4.0/ |
| Type: | article |
| URI: | http://hdl.handle.net/2115/81229 |
| Appears in Collections: | 獣医学院・獣医学研究院 (Graduate School of Veterinary Medicine / Faculty of Veterinary Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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