| Title: | Comparison of Health-Related Quality of Life Between Japanese and American Patients with Bladder Cancer as Measured by a Newly Developed Japanese Version of the Bladder Cancer Index |
| Authors: | Osawa, Takahiro Browse this author →KAKEN DB |
| Wei, John T. Browse this author |
| Abe, Takashige Browse this author |
| Honda, Michitaka Browse this author |
| Rew, Karl T. Browse this author |
| Dunn, Rod Browse this author |
| Yamada, Shuhei Browse this author |
| Furumido, Jun Browse this author |
| Kikuchi, Hiroshi Browse this author |
| Matsumoto, Ryuji Browse this author |
| Sato, Yasuyuki Browse this author |
| Harabayashi, Toni Browse this author |
| Takada, Norikata Browse this author |
| Minami, Keita Browse this author |
| Morita, Ken Browse this author |
| Kashiwagi, Akira Browse this author |
| Fukuhara, Shunichi Browse this author |
| Murai, Sachiyo Browse this author |
| Ito, Yoichi M. Browse this author |
| Ogasawara, Katsuhiko Browse this author |
| Shinohara, Nobuo Browse this author |
| Keywords: | Bladder cancer |
| quality of life |
| bladder cancer index |
| cancer survivor |
| Issue Date: | 19-Mar-2021 |
| Publisher: | IOS Press |
| Journal Title: | Bladder Cancer |
| Volume: | 7 |
| Issue: | 1 |
| Start Page: | 61 |
| End Page: | 69 |
| Publisher DOI: | 10.3233/BLC-200359 |
| Abstract: | INTRODUCTION: The aim of this study is to characterize health related quality of life (HRQOL) in Japanese patients after bladder cancer surgery and to perform cross-cultural comparison between Japanese and American patients. METHODS: Firstly, we cross-sectionally assessed HRQOL of 371 patients in Japan using the Bladder Cancer Index (BCI- Japanese). HRQOL of the four groups of patients (native bladder without intravesical therapy, native bladder with intravesical therapy, cystectomy with ileal conduit, and cystectomy with neobladder) were assessed. Secondly, we compared the Japanese with the American cohort (n = 315) from the original BCI paper. After adjusting for age and gender, the differences in each BCI subdomain score was analyzed. RESULTS: Among Japanese patients, the urinary domain function score was significantly lower among the cystectomy with neobladder group, compared to the cystectomy with ileal conduit group (p < 0. 01). Despite this, the urinary bother was comparable between the two groups. Although there were apparent differences between Japanese and American patients, there were few differences in Urinary and Bowel HRQOL. In three of the four treatment groups (other than native bladder with intravesical therapy), Japanese patients were more likely than Americans to report poor sexual function (p < 0.05). However, Japanese patients were less likely than Americans to be bothered by their lower sexual function, regardless of treatment (p <0.05). CONCLUSIONS: HRQOL outcomes following treatment of bladder cancer in Japan are comparable to those in the USA, except for sexual functioning and sexual bother. The BCI can be used for cross-cultural assessments of HRQOL in bladder cancer patients. |
| Type: | article |
| URI: | http://hdl.handle.net/2115/81586 |
| Appears in Collections: | 北海道大学病院 (Hokkaido University Hospital) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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