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Hypertensive Disorders during Pregnancy (HDP), Maternal Characteristics, and Birth Outcomes among Japanese Women : A Hokkaido Study

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Title: Hypertensive Disorders during Pregnancy (HDP), Maternal Characteristics, and Birth Outcomes among Japanese Women : A Hokkaido Study
Authors: Poudel, Kritika Browse this author
Kobayashi, Sumitaka Browse this author
Miyashita, Chihiro Browse this author
Ikeda-Araki, Atsuko Browse this author
Tamura, Naomi Browse this author
Ait Bamai, Yu Browse this author
Itoh, Sachiko Browse this author
Yamazaki, Keiko Browse this author
Masuda, Hideyuki Browse this author
Itoh, Mariko Browse this author
Ito, Kumiko Browse this author
Kishi, Reiko Browse this author →KAKEN DB
Keywords: hypertensive disorders during pregnancy
birth outcomes
cohort study
Issue Date: Apr-2021
Publisher: MDPI
Journal Title: International journal of environmental research and public health
Volume: 18
Issue: 7
Start Page: 3342
Publisher DOI: 10.3390/ijerph18073342
Abstract: Hypertension during pregnancy causes a greater risk of adverse birth outcomes worldwide; however, formal evidence of hypertensive disorders during pregnancy (HDP) in Japan is limited. We aimed to understand the association between maternal characteristics, HDP, and birth outcomes. In total, 18,833 mother-infant pairs were enrolled in the Hokkaido study on environment and children's health, Japan, from 2002 to 2013. Medical records were used to identify hypertensive disorders and birth outcomes, namely, small for gestational age (SGA), SGA at full term (term-SGA), preterm birth (PTB), and low birth weight (LBW). The prevalence of HDP was 1.9%. Similarly, the prevalence of SGA, term-SGA, PTB, and LBW were 7.1%, 6.3%, 7.4%, and 10.3%, respectively. The mothers with HDP had increased odds of giving birth to babies with SGA (2.13; 95% Confidence Interval (CI): 1.57, 2.88), PTB (3.48; 95%CI: 2.68, 4.50), LBW (3.57; 95%CI: 2.83, 4.51) than normotensive pregnancy. Elderly pregnancy, low and high body mass index, active and passive smoking exposure, and alcohol consumption were risk factors for different birth outcomes. Therefore, it is crucial for women of reproductive age and their families to be made aware of these risk factors through physician visits, health education, and various community-based health interventions.
Type: article
Appears in Collections:環境健康科学研究教育センター (Center for Environmental and Health Sciences) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

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