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Chronic Diarrhea as the Presenting Feature of Amyloidosis with Multiple Myeloma: A Case Report Diagnosed by a Myocardial Biopsy
| Title: | Chronic Diarrhea as the Presenting Feature of Amyloidosis with Multiple Myeloma: A Case Report Diagnosed by a Myocardial Biopsy |
| Authors: | Otagiri, Shinsuke Browse this author | | Nakajima, Sae Browse this author | | Katsurada, Takehiko Browse this author →KAKEN DB | | Sakurai, Kensuke Browse this author | | Yamanashi, Kana Browse this author | | Are, Takahide Browse this author | | Takakuwa, Emi Browse this author | | Mitsuhashi, Ibmoko Browse this author | | Sakamoto, Naoya Browse this author |
| Keywords: | amyloidosis | | bone marrow | | chronic diarrhea | | multiple myeloma | | myocardial biopsy |
| Issue Date: | 15-Apr-2021 |
| Publisher: | 日本内科学会(The Japanese Society of Internal Medicine) |
| Journal Title: | Internal medicine |
| Volume: | 60 |
| Issue: | 8 |
| Start Page: | 1197 |
| End Page: | 1203 |
| Publisher DOI: | 10.2169/internalmedicine.6038-20 |
| Abstract: | A 73-year-old woman with a history of diarrhea for one year and other various symptoms was admitted to our hospital. Gastrointestinal endoscopy that included enteroscopy with multiple biopsies was performed. However, no significant findings were observed. Electrocardiography showed low voltage in all limb leads, and an echocardiogram showed thickened cardiac walls with granular sparkling pattern. A myocardial biopsy revealed amyloidosis, and a bone marrow biopsy showed multiple myeloma. This case suggests that we should suspect the possibility of amyloidosis in a patient with diarrhea and various symptoms involving multiple organ systems. Additionally, electrocardiograms and echocardiograms should be performed even when gastrointestinal biopsies reveal negative results. |
| Type: | article |
| URI: | http://hdl.handle.net/2115/82000 |
| Appears in Collections: | 北海道大学病院 (Hokkaido University Hospital) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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