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Impacts of the urinary sodium-to-potassium ratio, sleep efficiency, and conventional risk factors on home hypertension in a general Japanese population

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Title: Impacts of the urinary sodium-to-potassium ratio, sleep efficiency, and conventional risk factors on home hypertension in a general Japanese population
Authors: Hirata, Takumi Browse this author →KAKEN DB
Kogure, Mana Browse this author
Tsuchiya, Naho Browse this author
Miyagawa, Ken Browse this author
Narita, Akira Browse this author
Nochioka, Kotaro Browse this author
Uruno, Akira Browse this author
Obara, Taku Browse this author
Nakamura, Tomohiro Browse this author
Nakaya, Naoki Browse this author
Metoki, Hirohito Browse this author
Kikuya, Masahiro Browse this author
Sugawara, Junichi Browse this author
Kuriyama, Shinichi Browse this author
Tsuji, Ichiro Browse this author
Kure, Shigeo Browse this author
Hozawa, Atsushi Browse this author
Keywords: Population attributable fraction
Home hypertension
Risk factor
Public health
Japanese
Issue Date: Jul-2021
Publisher: Springer Nature
Journal Title: Hypertension Research
Volume: 44
Issue: 7
Start Page: 858
End Page: 865
Publisher DOI: 10.1038/s41440-021-00628-y
Abstract: Recently, a high urinary sodium-to-potassium (Na/K) ratio and reduced sleep efficiency, in addition to conventional risk factors (obesity and excess alcohol intake), have been identified as risk factors for hypertension. We estimated the population attributable fraction (PAF) for home hypertension due to these risk factors in a general Japanese population. We conducted a cross-sectional study including 1384 participants (393 men and 991 women) to estimate the odds ratio (OR) and 95% confidence interval (CI) for the presence of any of the conventional risk factors using multivariable logistic regression analyses. The models were adjusted for sex, age, smoking status, and log-transformed average daily steps. We also estimated the OR and 95% CI for the presence of any of the overall risk factors. Furthermore, we calculated the PAF due to these risk factors. The results showed that the prevalence of home hypertension was 39.0% (540/1384). The presence of any of the conventional risk factors, as well as any of the overall risk factors, was significantly associated with an increased prevalence of hypertension (OR 2.80, 95% CI 2.15-3.65; OR 2.50, 95% CI 1.93-3.22, respectively). The PAF for hypertension due to the presence of any of the conventional risk factors and the PAF due to the presence of any of the overall risk factors were 30.2% and 39.0%, respectively. In conclusion, the impact of the overall risk factors, including the urinary Na/K ratio and sleep efficiency, on home hypertension was higher than that of conventional risk factors alone. The management of the urinary Na/K ratio and sleep efficiency as well as conventional risk factors might be important in the management of blood pressure.
Rights: https://creativecommons.org/licenses/by/4.0/
Type: article
URI: http://hdl.handle.net/2115/82094
Appears in Collections:医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

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