|
Hokkaido University Collection of Scholarly and Academic Papers >
Graduate School of Medicine / Faculty of Medicine >
Peer-reviewed Journal Articles, etc >
Continuation of antithrombotic therapy increases minor bleeding but does not increase the risk other morbidities in open inguinal hernia repair : A propensity score-matched analysis
| Title: | Continuation of antithrombotic therapy increases minor bleeding but does not increase the risk other morbidities in open inguinal hernia repair : A propensity score-matched analysis |
| Authors: | Poudel, S. Browse this author | | Miyazaki, K. Browse this author | | Hirano, S. Browse this author →KAKEN DB |
| Keywords: | Open inguinal hernia repair | | Antithrombotic therapy | | Anticoagulation | | Antiplatelets |
| Issue Date: | Aug-2020 |
| Publisher: | Springer |
| Journal Title: | Hernia |
| Volume: | 24 |
| Issue: | 4 |
| Start Page: | 857 |
| End Page: | 865 |
| Publisher DOI: | 10.1007/s10029-020-02169-8 |
| Abstract: | Purpose An aging population has led to an increased number of patients with cardiovascular comorbidities requiring antithrombotic therapy. Perioperatively, surgeons should consider the increased risk of bleeding and thrombotic events in patients continuing or discontinuing these medications. We aimed to analyze the safety of continued antithrombotic therapy during open inguinal hernia repair. Methods In this single-center, retrospective study, 4870 adult patients who underwent open inguinal hernia repair surgery by the same surgeon from 2008 January to 2019 March were included. Patients who underwent surgery while continuing antithrombotic therapy were included in the antithrombin group (n = 523) while those who were not under any antithrombotic therapy during the surgery were included in the control group (n = 4333). Using propensity score-matching, we then selected patients from each group with similar backgrounds. Surgery time, anesthesia time, postoperative bleeding, reoperation, and thrombotic event data were compared between the groups. Subgroup analysis based on the type of medications used was performed within the antithrombin group. Results Ten patients in the antithrombin group and seven patients in the control group experienced postoperative bleeding (p < 0.001). The rate of postoperative bleeding was the highest in patients taking multiple medications. However, most were managed conservatively. Three patients from the antithrombin group experienced thrombotic events postoperatively (p = 0.001). Conclusions Patients receiving continued antithrombotic therapy had an increased risk of minor postoperative bleeding; however, they are a high-risk group for thrombotic events. |
| Rights: | This is a post-peer-review, pre-copyedit version of an article published in Hernia. The final authenticated version is available online at: http://dx.doi.org/10.1007/s10029-020-02169-8. |
| Type: | article (author version) |
| URI: | http://hdl.handle.net/2115/82342 |
| Appears in Collections: | 医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
|
Submitter: 平野 聡
|
