| Title: | Predictive value of gadoxetic acid enhanced magnetic resonance imaging for posthepatectomy liver failure after a major hepatectomy |
| Authors: | Orimo, Tatsuya Browse this author →KAKEN DB |
| Kamiyama, Toshiya Browse this author →KAKEN DB |
| Kamachi, Hirofumi Browse this author →KAKEN DB |
| Shimada, Shingo Browse this author →KAKEN DB |
| Nagatsu, Akihisa Browse this author |
| Asahi, Yoh Browse this author |
| Sakamoto, Yuzuru Browse this author |
| Abo, Daisuke Browse this author →KAKEN DB |
| Taketomi, Akinobu Browse this author →KAKEN DB |
| Keywords: | posthepatectomy liver failure |
| magnetic resonance imaging |
| hepatectomy |
| liver resection |
| Issue Date: | Aug-2020 |
| Publisher: | John Wiley & Sons |
| Journal Title: | Journal of hepato-biliary-pancreatic sciences |
| Volume: | 27 |
| Issue: | 8 |
| Start Page: | 531 |
| End Page: | 540 |
| Publisher DOI: | 10.1002/jhbp.769 |
| Abstract: | Background We assessed the usefulness of gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid enhanced magnetic resonance imaging for the prediction of posthepatectomy liver failure (PHLF) after a major hepatectomy. Methods We reviewed 140 cases involving a hepatectomy of two or more sections between 2010 and 2016 (study cohort). We used the standardized remnant hepatocellular uptake index (SrHUI) which was calculated by: SrHUI = future remnant liver volume x [(signal intensity of remnant liver on hepatobiliary phase images/signal intensity of spleen on hepatobiliary phase images) - 1]/body surface area. Validation of the SrHUI was performed in another cohort of 52 major hepatectomy cases between 2017 and 2018 (validation cohort). Results The SrHUI of patients with PHLF was significantly lower than that of non-PHLF cases. Receiver operating characteristic analysis and the Youden index revealed that the SrHUI cutoff value for the prediction of PHLF and PHLF grade >= B were 0.313 L/m(2)and 0.257 L/m(2), respectively. In the validation cohort, the cutoff value of SrHUI for the prediction of PHLF or PHLF grade >= B had a sensitivity of 75.0% or 88.8%, and specificity of 78.1% or 91.6%, respectively. Conclusions The SrHUI value is a predictor for PHLF after a major hepatectomy. |
| Rights: | "This is the peer reviewed version of the following article: Orimo, T, Kamiyama, T, Kamachi, H, et al. Predictive value of gadoxetic acid enhanced magnetic resonance imaging for posthepatectomy liver failure after a major hepatectomy. J Hepatobiliary Pancreat Sci. 2020; 27: 531– 540, which has been published in final form at https://doi.org/10.1002/jhbp.769. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions." |
| Type: | article (author version) |
| URI: | http://hdl.handle.net/2115/82348 |
| Appears in Collections: | 医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
|
