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Nonsteroidal anti-inflammatory drugs use in patients with chronic kidney disease are often prescribed from different clinicians than those who diagnosed them

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Please use this identifier to cite or link to this item:http://hdl.handle.net/2115/82349

Title: Nonsteroidal anti-inflammatory drugs use in patients with chronic kidney disease are often prescribed from different clinicians than those who diagnosed them
Authors: Imai, Shungo Browse this author →KAKEN DB
Momo, Kenji Browse this author →KAKEN DB
Kashiwagi, Hitoshi Browse this author →KAKEN DB
Miyai, Takayuki Browse this author
Sugawara, Mitsuru Browse this author →KAKEN DB
Takekuma, Yoh Browse this author →KAKEN DB
Keywords: chronic kidney disease
insurance claim
nonsteroidal anti-inflammatory drug
pharmacoepidemiology
Issue Date: Aug-2020
Publisher: John Wiley & Sons
Journal Title: Pharmacoepidemiology and drug safety
Volume: 29
Issue: 8
Start Page: 873
End Page: 880
Publisher DOI: 10.1002/pds.5027
Abstract: Purpose When prescribing nonsteroidal anti-inflammatory drugs (NSAIDs) for chronic kidney disease (CKD), patients' pathology and concomitant medications should be considered. In our pharmaceutical experience, NSAIDs are often prescribed by departments that are different from those that diagnosed CKD. That is, NSAIDs may be prescribed for patients without the advice of the clinicians who diagnosed them. In this study, we aimed to elucidate how frequently such cases occur. Methods We used the large health insurance claims database constructed by JMDC Inc., Tokyo. We evaluated the proportions of CKD diagnosis and NSAID prescription by different clinical departments and institutions. Results A total of 224 014 out-patients were included in the analysis; they were divided into CKD (n = 1501) and non-CKD groups (n = 222 513). The internal medicine departments diagnosed CKD most frequently (74.8% of the patients) and surgical departments rarely diagnosed CKD. However, the proportion of prescribed NSAIDs was high in other departments, especially surgical departments. In the CKD group, 50.4% of the patients received CKD diagnosis and NSAID prescription from different clinical departments; 72.8% of the patients received a diagnosis and prescription from different medical institutions. Conclusion Our study revealed that NSAIDs are often prescribed to patients with CKD from different clinicians than those who diagnosed them.
Rights: This is the peer reviewed version of the following article: Imai, S, Momo, K, Kashiwagi, H, Miyai, T, Sugawara, M, Takekuma, Y. Nonsteroidal anti‐inflammatory drugs use in patients with chronic kidney disease are often prescribed from different clinicians than those who diagnosed them. Pharmacoepidemiol Drug Saf. 2020; 29: 873– 880, which has been published in final form at https://doi.org/10.1002/pds.5027. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.
Type: article (author version)
URI: http://hdl.handle.net/2115/82349
Appears in Collections:北海道大学病院 (Hokkaido University Hospital) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 武隈 洋

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