HUSCAP logo Hokkaido Univ. logo

Hokkaido University Collection of Scholarly and Academic Papers >
Graduate School of Medicine / Faculty of Medicine >
Peer-reviewed Journal Articles, etc >

Immune Thrombocytopenia Treated with Intravenous Erythromycin

Files in This Item:
GMJ 32(4) 577-579.pdf1.12 MBPDFView/Open
Please use this identifier to cite or link to this item:

Title: Immune Thrombocytopenia Treated with Intravenous Erythromycin
Authors: Ohe, Masashi Browse this author
Furuya, Ken Browse this author
Goudarzi, Houman Browse this author →KAKEN DB
Keywords: Immune thrombocytopenia
Issue Date: 9-Sep-2021
Publisher: Gazi University
Journal Title: Gazi Medical Journal
Volume: 32
Issue: 4
Start Page: 577
End Page: 579
Publisher DOI: 10.12996/gmj.2021.129
Abstract: Macrolides (MACs) such as clarithromycin (CAM) and erythromycin (EM) have immunomodulatory effects as well as anti-bacterial activity. In consideration of immunomodulatory effects, we report a patient with primary immune thrombocytopenia (ITP) treated with corticosteroids (CSs) combined with MACs. An 84-year-old woman with ITP was admitted to our hospital for further examination of reduced platelet counts. After admission, the patient was diagnosed with exacerbated primary ITP. The patient was successfully treated with intravenous immunoglobulin. However, the patient was unsuccessfully treated with CSs (i.e., prednisolone (PSL)and methyl PSL) combined with CAM. Eltrombopag (ELT), a thrombopoietin-receptor agonist, was successfully added. However, the patient suffered from aspiration pneumonia, making it impossible to administer oral drugs (i.e., PSL, CAM, and ELT). Alternatively, she was successfully treated with intravenous PSL combined with intravenous EM. This case shows that the efficacy of intravenous EM treatment may be higher than that of oral CAM treatment.
Type: article
Appears in Collections:医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Export metadata:

OAI-PMH ( junii2 , jpcoar_1.0 )

MathJax is now OFF:


 - Hokkaido University