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Validation of Fully Automatic Quantitative Software for Finger Joint Space Narrowing Progression for Rheumatoid Arthritis Patients
| Title: | Validation of Fully Automatic Quantitative Software for Finger Joint Space Narrowing Progression for Rheumatoid Arthritis Patients |
| Authors: | Narisawa, Chiaki Browse this author | | Sutherland, Kenneth Browse this author →KAKEN DB | | Lu, Yutong Browse this author | | Furusaki, Akira Browse this author | | Sagawa, Akira Browse this author | | Kamishima, Tamotsu Browse this author →KAKEN DB |
| Keywords: | Rheumatoid arthritis | | Radiography | | Joint space narrowing | | Computer-based analysis |
| Issue Date: | 28-Sep-2020 |
| Publisher: | Springer |
| Journal Title: | Journal of digital imaging |
| Volume: | 33 |
| Issue: | 6 |
| Start Page: | 1387 |
| End Page: | 1392 |
| Publisher DOI: | 10.1007/s10278-020-00390-6 |
| Abstract: | In rheumatoid arthritis (RA), the radiographic progression of joint space narrowing (JSN) is evaluated using visual assessments. However, those methods are complicated and time-consuming. We developed an automatic system that can detect joint locations and compute the joint space difference index (JSDI), which was defined as the chronological change in JSN between two radiographs. The purpose of this study was to establish the validity of the software that automatically evaluates the temporal change of JSN. This study consisted of 39 patients with RA. All patients were treated with tocilizumab and underwent hand radiography (left and right hand separately) at 0, 6, and 12 months. The JSN was evaluated using mTSS (modified Total Sharp Score) by one musculoskeletal radiologist as well as our automatic system. Software measurement showed that JSDI between 0 and 12 months was significantly higher than that between 0 and 6 months (p< 0.01). While, there was no significant difference in mTSS between 0, 6, and 12 months. The group with higher disease activity at 0 months had significantly higher JSDI between 0 and 6 months than that with lower disease activity (p= 0.02). The automatic software can evaluate JSN progression of RA patients in the finger joint on X-ray. |
| Rights: | This is a post-peer-review, pre-copyedit version of an article published in Journal of Digital Imaging. The final authenticated version is available online at: https://doi.org/10.1007/s10278-020-00390-6 |
| Type: | article (author version) |
| URI: | http://hdl.handle.net/2115/82767 |
| Appears in Collections: | 保健科学院・保健科学研究院 (Graduate School of Health Sciences / Faculty of Health Sciences) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 神島 保
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