| Title: | Risk factors for dysfunction of preoperative endoscopic biliary drainage for malignant hilar biliary obstruction |
| Authors: | Sugiura, Ryo Browse this author |
| Kuwatani, Masaki Browse this author →KAKEN DB |
| Kato, Shin Browse this author |
| Kawakubo, Kazumichi Browse this author →KAKEN DB |
| Kamachi, Hirofumi Browse this author →KAKEN DB |
| Taketomi, Akinobu Browse this author →KAKEN DB |
| Noji, Takehiro Browse this author →KAKEN DB |
| Okamura, Keisuke Browse this author →KAKEN DB |
| Hirano, Satoshi Browse this author →KAKEN DB |
| Sakamoto, Naoya Browse this author →KAKEN DB |
| Keywords: | endoscopic biliary drainage |
| preoperative biliary drainage |
| malignant hilar biliary obstruction |
| hilar cholangiocarcinoma |
| gall bladder cancer |
| Issue Date: | Nov-2020 |
| Publisher: | John Wiley & Sons |
| Journal Title: | Journal of hepato-biliary-pancreatic sciences |
| Volume: | 27 |
| Issue: | 11 |
| Start Page: | 851 |
| End Page: | 859 |
| Publisher DOI: | 10.1002/jhbp.778 |
| Abstract: | Background Few studies have focused on the risk factors for dysfunction of endoscopic biliary drainage (EBD) in preoperative patients with malignant hilar biliary obstruction (MHBO). Methods We searched the database between February 2011 and December 2018 and identified patients with MHBO who underwent radical operation. The rate of dysfunction of the initial EBD, risk factors for dysfunction of the initial EBD and survival after surgery were retrospectively evaluated. Results We analyzed a total of 131 patients [95 males (72.5%); mean age, 69.5 (+/- 7.3) years; Bismuth-Corlette classification (BC) I/II/IIIa/IIIb/IV, 50/26/22/17/16; hilar cholangiocarcinoma/gall bladder cancer, 115/16]. Dysfunction of the initial EBD occurred in 28 patients (21.4%). The cumulative incidences of dysfunction of the initial EBD in all patients were 18.4%, 38.2% and 47.0% at 30, 60 and 90 days, respectively (Kaplan-Meier method). The rate of dysfunction of the initial EBD increased in patients with BC-IV (P = .03). Multivariate analysis showed that BC-IV and pre-EBD cholangitis were significantly associated with the occurrence of dysfunction of the initial EBD. Survival rates were not significantly different according to the initial biliary drainage methods and presence/absence of the initial EBD dysfunction. Conclusions Dysfunction of the initial EBD frequently occurs in patients with the BC-IV and those with pre-EBD cholangitis. |
| Rights: | This is the peer reviewed version of the following article: Sugiura, R, Kuwatani, M, Kato, S, et al. Risk factors for dysfunction of preoperative endoscopic biliary drainage for malignant hilar biliary obstruction. J Hepatobiliary Pancreat Sci. 2020; 27: 851– 859., which has been published in final form at https://doi.org/10.1002/jhbp.778. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. |
| Type: | article (author version) |
| URI: | http://hdl.handle.net/2115/83141 |
| Appears in Collections: | 北海道大学病院 (Hokkaido University Hospital) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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