HUSCAP logo Hokkaido Univ. logo

Hokkaido University Collection of Scholarly and Academic Papers >
Graduate School of Medicine / Faculty of Medicine >
Peer-reviewed Journal Articles, etc >

Performance of Qualitative and Quantitative Antigen Tests for SARS-CoV-2 Using Saliva

Files in This Item:

The file(s) associated with this item can be obtained from the following URL:

Title: Performance of Qualitative and Quantitative Antigen Tests for SARS-CoV-2 Using Saliva
Authors: Yokota, Isao Browse this author →KAKEN DB
Sakurazawa, Takayo Browse this author
Sugita, Junichi Browse this author →KAKEN DB
Iwasaki, Sumio Browse this author
Yasuda, Keiko Browse this author
Yamashita, Naoki Browse this author
Fujisawa, Shinichi Browse this author
Nishida, Mutsumi Browse this author →KAKEN DB
Konno, Satoshi Browse this author →KAKEN DB
Teshima, Takanori Browse this author →KAKEN DB
Keywords: SARS-CoV-2
Issue Date: Sep-2021
Publisher: MDPI
Journal Title: Infectious Disease Reports
Volume: 13
Issue: 3
Start Page: 742
End Page: 747
Publisher DOI: 10.3390/idr13030069
Abstract: The rapid detection of SARS-CoV-2 is critical for the prevention of disease outbreaks. Antigen tests such as immunochromatographic assay (ICA) and chemiluminescent enzyme immunoassay (CLEIA) can yield results more quickly than PCR. We evaluated the performance of ICA and CLEIA using 34 frozen PCR-positive (17 saliva samples and 17 nasopharyngeal swabs [NPS]) and 309 PCR-negative samples. ICA detected SARS-CoV-2 in only 14 (41%) samples, with positivity rates of 24% in saliva and 59% in NPS. Notably, ICA detected SARS-CoV-2 in 5 of 6 samples collected within 4 days after symptom onset. CLEIA detected SARS-CoV-2 in 31 (91%) samples, with a positivity of 82% in saliva and 100% in NPS. These results suggest that the use of ICA should be limited to an earlier time after symptom onset and CLEIA is more sensitive and can be used in situations where quick results are required.
Type: article
Appears in Collections:医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Export metadata:

OAI-PMH ( junii2 , jpcoar_1.0 )

MathJax is now OFF:


 - Hokkaido University