|
Hokkaido University Collection of Scholarly and Academic Papers >
Graduate School of Medicine / Faculty of Medicine >
Peer-reviewed Journal Articles, etc >
Patients with marginal zone dural lymphoma successfully treated with rituximab and bendamustine : A report of two cases
| Title: | Patients with marginal zone dural lymphoma successfully treated with rituximab and bendamustine : A report of two cases |
| Authors: | Tsutsumi, Yutaka Browse this author | | Ito, Shinichi Browse this author | | Nagai, Jun Browse this author | | Tateno, Takahiro Browse this author | | Teshima, Takanori Browse this author →KAKEN DB |
| Keywords: | dural mucosa-associated lymphoid tissue | | bendamustine | | central nervous system |
| Issue Date: | Oct-2021 |
| Publisher: | Spandidos Publications |
| Journal Title: | Molecular and clinical oncology |
| Volume: | 15 |
| Issue: | 4 |
| Start Page: | 208 |
| Publisher DOI: | 10.3892/mco.2021.2371 |
| Abstract: | Primary dural low-grade marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT) is a rare disease whose main treatment has been local surgery or radiotherapy. Until now, there have been no cases of dural MALT lymphoma treatment of a patient with several relapses or systemic disease. The present study included two patients with dural MALT lymphoma who had several relapses or systemic disease. Since local therapy was not enough to control the disease for these patients, they were treated with systemic chemotherapy. The patients were administered rituximab (375 mg/m(2)) and two days of bendamustine (90 mg/m(2)). Both patients recovered from their clinical symptoms immediately, and their tumors were reduced. During and after rituximab and bendamustine therapy, no central nervous system (CNS) metastasis or cerebrospinal fluid invasion of MALT were observed. The current approach using rituximab and bendamustine treatment was effective against dural MALT lymphoma and may prevent its invasion of the CNS. |
| Type: | article |
| URI: | http://hdl.handle.net/2115/83244 |
| Appears in Collections: | 医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
|
|
