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Associations of Cognitive Complaints and Depressive Symptoms with Health-Related Quality of Life and Perceived Overall Health in Japanese Adult Volunteers
| Title: | Associations of Cognitive Complaints and Depressive Symptoms with Health-Related Quality of Life and Perceived Overall Health in Japanese Adult Volunteers |
| Authors: | Toyoshima, Kuniyoshi Browse this author | | Inoue, Takeshi Browse this author →KAKEN DB | | Baba, Toshiaki Browse this author →KAKEN DB | | Masuya, Jiro Browse this author →KAKEN DB | | Ichiki, Masahiko Browse this author →KAKEN DB | | Fujimura, Yota Browse this author | | Kusumi, Ichiro Browse this author →KAKEN DB |
| Keywords: | cognitive complaints | | depressive symptoms | | health-related quality of life | | path analysis | | mediator |
| Issue Date: | Sep-2021 |
| Publisher: | MDPI |
| Journal Title: | International journal of environmental research and public health |
| Volume: | 18 |
| Issue: | 18 |
| Start Page: | 9647 |
| Publisher DOI: | 10.3390/ijerph18189647 |
| Abstract: | Cognitive complaints, defined as perceived cognitive dysfunction in daily living, are associated with depressive symptoms. The associations of cognitive complaints and depressive symptoms with health-related quality of life (HRQoL) and perceived overall health in Japanese adults remains unknown. To investigate these relationships, we evaluated a convenience sample of 525 Japanese adult volunteers (Mage: 41.3 +/- 11.7; 238 male and 287 female). We used the Cognitive Complaints in Bipolar Disorder Rating Assessment (evaluating cognitive complaints), Patient Health Questionnaire-9 (evaluating depressive symptoms), EuroQol-5 Dimension-5 Level (EQ-5D-5L; evaluating HRQoL), and EuroQol-Visual Analogue Scale (EQ-VAS; evaluating perceived overall health). Our path analyses suggested that both cognitive complaints and depressive symptoms had significant total effects on HRQoL and perceived overall health. Furthermore, cognitive complaints were not significantly associated directly with HRQoL and perceived overall health, whereas cognitive complaints were significantly associated with HRQoL and perceived overall health indirectly via depressive symptoms. Depressive symptoms were significantly associated directly with HRQoL and perceived overall health. This study suggests that depressive symptoms may mediate the associations of cognitive complaints with HRQoL and perceived overall health. Thus, to address the HRQoL and perceived overall health associated with cognitive complaints, evaluation and intervention for depressive symptoms may be useful in public health. |
| Type: | article |
| URI: | http://hdl.handle.net/2115/83248 |
| Appears in Collections: | 医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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