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Hokkaido University Collection of Scholarly and Academic Papers >
Graduate School of Fisheries Sciences / Faculty of Fisheries Sciences >
Peer-reviewed Journal Articles, etc >
Identification of ACE inhibitory peptides from red alga Mazzaella japonica
| Title: | Identification of ACE inhibitory peptides from red alga Mazzaella japonica |
| Authors: | Kumagai, Yuya Browse this author →KAKEN DB | | Kitade, Yumi Browse this author | | Kobayashi, Manami Browse this author | | Watanabe, Kei Browse this author | | Kurita, Hiroki Browse this author | | Takeda, Hirohumi Browse this author | | Yasui, Hajime Browse this author →KAKEN DB | | Kishimura, Hideki Browse this author →KAKEN DB |
| Keywords: | ACE inhibitory activity | | Antihypertension | | Red alga | | Mazzaella japonica | | Protein hydrolysate |
| Issue Date: | 30-Nov-2021 |
| Publisher: | Springer |
| Journal Title: | European Food Research and Technology |
| Volume: | 246 |
| Start Page: | 2225 |
| End Page: | 2231 |
| Publisher DOI: | 10.1007/s00217-020-03567-z |
| Abstract: | Angiotensin I converting enzyme (ACE) inhibition is one of the key factors for cardiovascular disease, and inhibition of ACE activity is related to the prevention of high blood pressure. Until now, some ACE inhibitory peptides have been found in the protein hydrolysates of red algae, and most of them were derived from phycobiliproteins and rubisco. In this study, we modified the preparation method to evaluate the potential of ACE inhibitory activity from protein hydrolysate of red algaMazzaella japonicaexcept for phycobiliproteins and rubisco. As a result, we identified 11 peptides (YRD, VSEGLD, TIMPHPR, GGPAT, SSNDYPI, SRIYNVKSNG, VDAHY, CPYDWV, YGDPDHY, NLGN and DFGVPGHEP) in the hydrolysate by the reversed phase-HPLC and MALDI-TOF/MS/MS. Among them, YRD would be derived from phycoerythrin alpha-subunit. However, the others would be from other proteins encoded in chloroplast or nuclear genomes. This study revealed that not only phycobiliproteins and rubisco but also the other proteins in red algae have the potential for the source of ACE inhibitory peptide. |
| Rights: | This is a post-peer-review, pre-copyedit version of an article published in European Food Research and Technology. The final authenticated version is available online at: http://dx.doi.org/10.1007/s00217-020-03567-z |
| Type: | article (author version) |
| URI: | http://hdl.handle.net/2115/83358 |
| Appears in Collections: | 水産科学院・水産科学研究院 (Graduate School of Fisheries Sciences / Faculty of Fisheries Sciences) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 岸村 栄毅
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