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What are the Optimal Renal Ultrasound Parameters for Detecting Small Kidney in Young Children?

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Title: What are the Optimal Renal Ultrasound Parameters for Detecting Small Kidney in Young Children?
Authors: Kon, Masafumi Browse this author
Nakamura, Michiko Browse this author
Moriya, Kimihiko Browse this author
Nishimura, Yoko Browse this author
Hirata, Yurie Browse this author
Nishida, Mutsumi Browse this author
Higuchi, Madoka Browse this author
Kitta, Takeya Browse this author
Shinohara, Nobuo Browse this author →KAKEN DB
Keywords: small kidney
ultrasound
screening
cutoff value
Issue Date: 26-Oct-2021
Publisher: Dove Medical Press
Journal Title: Research and Reports in Urology
Volume: 13
Start Page: 767
End Page: 772
Publisher DOI: 10.2147/RRU.S318793
Abstract: Introduction: Recent guidelines do not recommend routine screening of vesicoureteral reflux after a first febrile urinary tract infection in children without abnormal findings on ultrasound or atypical/recurrent urinary tract infection. Currently, there are no clear ultra-sonographic parameters for detecting abnormalities in renal size, especially in young chil-dren. The aim of the present study was to determine an optimal cutoff value for detecting small kidney in children without apparent congenital anomalies except vesicoureteral reflux by retrospective chart review. Patients and Methods: Children aged <= 3 years who had undergone nuclear renal scans and ultrasound were enrolled. Small kidney was defined as split renal function of <40%. Optimal cutoff values of various ultrasonographic parameters for detecting small kidney were calculated. Results: Of the 69 children included in the present study, small kidney was identified in 20. There was a significant difference in renal size between each kidney in patients with small kidney, whereas there was no significant difference in those without small kidney. With a ratio of estimated renal area of 74.26%, maximum area under the curve with the highest sensitivity, specificity, positive predictive value, negative predictive value, and accuracy rate were obtained. In addition, simple measurement of renal length with a cutoff of 4.97 cm showed high specificity comparable with estimated renal area. Conclusion: Small kidney may be screened by two-dimensional measurement on ultrasono-graphic examination, even in young children. With the cutoff described, risk stratification or an individualized approach may be possible.
Type: article
URI: http://hdl.handle.net/2115/83360
Appears in Collections:医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

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