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Efficacy of rikkosan for primary burning mouth syndrome: a retrospective study

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Title: Efficacy of rikkosan for primary burning mouth syndrome: a retrospective study
Authors: Hato, Hiroyuki Browse this author
Sakata, Ken-ichiro Browse this author →KAKEN DB
Sato, Jun Browse this author →KAKEN DB
Asaka, Takuya Browse this author →KAKEN DB
Ohga, Noritaka Browse this author →KAKEN DB
Yamazaki, Yutaka Browse this author →KAKEN DB
Kitagawa, Yoshimasa Browse this author →KAKEN DB
Keywords: Burning mouth syndrome
Kampo medicine
Issue Date: 30-Oct-2021
Publisher: BioMed Central
Journal Title: BioPsychoSocial Medicine
Volume: 15
Issue: 1
Start Page: 19
Publisher DOI: 10.1186/s13030-021-00221-2
PMID: 34717696
Abstract: Background Burning mouth syndrome (BMS) is a chronic condition characterized by pain in the oral cavity. Kampo medicine is a traditional Japanese medical system that has its roots partly in ancient Chinese medicine. The purpose of this study is to evaluate the efficacy of rikkosan-a traditional Japanese herbal medicine (Kampo)-in the treatment of primary BMS. Main body A single-center retrospective study was conducted in 32 patients who were diagnosed with primary BMS and treated with rikkosan alone through gargling (2.5 g rikkosan dissolved in 50 mL hot water) three times daily. Patients were asked to evaluate their pain using a numerical rating scale (NRS) at first visit and after 1 month. One patient had stomatitis as a side effect after gargling with rikkosan, however, no side effects were observed in other patients. Overall NRS scores decreased significantly between the first visit (7.6 +/- 2.7) and the 1-month visit (5.6 +/- 2.8). Conclusions Rikkosan may be an effective treatment for primary BMS.
Type: article
Appears in Collections:歯学院・歯学研究院 (Graduate School of Dental Medicine / Faculty of Dental Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

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