| Title: | Particle therapy using protons or carbon ions for cancer patients with cardiac implantable electronic devices (CIED) : a retrospective multi-institutional study |
| Authors: | Hashimoto, Takayuki Browse this author →KAKEN DB |
| Demizu, Yusuke Browse this author |
| Numajiri, Haruko Browse this author →KAKEN DB |
| Isobe, Tomonori Browse this author |
| Fukuda, Shigekazu Browse this author |
| Wakatsuki, Masaru Browse this author |
| Yamashita, Haruo Browse this author |
| Murayama, Shigeyuki Browse this author →KAKEN DB |
| Takamatsu, Shigeyuki Browse this author |
| Katoh, Hiroyuki Browse this author |
| Murata, Kazutoshi Browse this author |
| Kohno, Ryosuke Browse this author |
| Arimura, Takeshi Browse this author |
| Matsuura, Taeko Browse this author →KAKEN DB |
| Ito, Yoichi M. Browse this author →KAKEN DB |
| Keywords: | Proton beam therapy |
| Carbon ion therapy |
| Cardiac implantable electronic devices |
| Electrical reset |
| Secondary neutron |
| Issue Date: | 23-Dec-2021 |
| Publisher: | Springer |
| Journal Title: | Japanese journal of radiology |
| Volume: | 40 |
| Start Page: | 525 |
| End Page: | 533 |
| Publisher DOI: | 10.1007/s11604-021-01218-1 |
| Abstract: | Purpose To evaluate the outcomes of particle therapy in cancer patients with cardiac implantable electronic devices (CIEDs). Materials and methods From April 2001 to March 2013, 19,585 patients were treated with proton beam therapy (PBT) or carbon ion therapy (CIT) at 8 institutions. Of these, 69 patients (0.4%, PBT 46, CIT 22, and PBT + CIT 1) with CIEDs (64 pacemakers, 4 implantable cardioverter defibrillators, and 1 with a cardiac resynchronization therapy defibrillator) were retrospectively reviewed. All the patients with CIEDs in this study were treated with the passive scattering type of particle beam therapy. Results Six (13%) of the 47 PBT patients, and none of the 23 CIT patients experienced CIED malfunctions (p = 0.105). Electrical resets (7) and over-sensing (3) occurred transiently in 6 patients. The distance between the edge of the irradiation field and the CIED was not associated with the incidence of malfunctions in 20 patients with lung cancer. A larger field size had a higher event rate but the test to evaluate trends as not statistically significant (p = 0.196). Conclusion Differences in the frequency of occurrence of device malfunctions for patients treated with PBT and patients treated with CIT did not reach statistical significance. The present study can be regarded as a benchmark study about the incidence of malfunctioning of CIED in passive scattering particle beam therapy and can be used as a reference for active scanning particle beam therapy. |
| Type: | article |
| URI: | http://hdl.handle.net/2115/83675 |
| Appears in Collections: | 医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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